Gene: NOL4
Official Full Name: nucleolar protein 4provided by HGNC
Gene Summary: Predicted to enable RNA binding activity. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33928 | NOL4 Knockout cell line (HEK293) | Human | NOL4 | 1:3~1:6 | Negative | Online Inquiry |
NOL4 Gene Knockout Cell Lines are specifically engineered cellular models designed to investigate the function of the NOL4 gene, which plays a critical role in cellular processes such as ribosome biogenesis and stress response. These cell lines are created using advanced gene editing technologies, including CRISPR/Cas9, allowing for precise deletions of the NOL4 gene to elucidate its physiological roles and underlying mechanisms at a molecular level.
The primary function of NOL4 involves the modulation of various cellular stress responses, contributing to the regulation of cell survival and proliferation. By utilizing the NOL4 Gene Knockout Cell Lines, researchers can dissect the effects of NOL4 deficiency on cellular pathways, enabling a better understanding of its contributions to oncogenesis and other pathophysiological conditions. This functionality is essential for experimental models that aim to explore the gene's impact on disease states, including cancer development and neurological disorders.
The scientific importance of these cell lines lies in their application in both research and clinical settings. They serve as invaluable tools for drug discovery and validation, facilitating the screening of therapeutics targeting stress-related pathways. Furthermore, NOL4 knockout models can significantly advance our understanding of gene function, contributing to novel biomedical research focusing on gene-targeted therapies.
Advantages of using NOL4 Gene Knockout Cell Lines include their high specificity, consistent expression levels, and validated backgrounds, which surpass traditional knockdown techniques that can result in off-target effects. The precision of knockout technologies ensures a reliable study of NOL4-related cellular dynamics.
For researchers, clinicians, and biopharmaceutical companies, these cell lines represent a vital resource in the quest to unlock the complexities of gene function and its implications in health and disease. The potential applications span therapeutic development and the exploration of fundamental biological questions, enhancing the value they provide to scientific inquiry.
With our dedication to producing high-quality biological products, our company leverages cutting-edge technology and expertise in gene editing to deliver innovative tools such as the NOL4 Gene Knockout Cell Lines, empowering your research efforts and driving forward the understanding of critical biological mechanisms.
Please note that all services are for research use only. Not intended for any clinical use.
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