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NME5 Knockout Cell Lines

Gene: NME5

Official Full Name: NME/NM23 family member 5provided by HGNC

Gene Summary: Enables 3'-5' exonuclease activity. Involved in spermatid development. Predicted to be located in 9+2 motile cilium. Predicted to be part of radial spoke. Predicted to be active in cilium. Implicated in primary ciliary dyskinesia. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34219 NME5 Knockout cell line (HCT 116) Human NME5 1:2~1:4 Negative Online Inquiry
KO34220 NME5 Knockout cell line (HEK293) Human NME5 1:3~1:6 Negative Online Inquiry

Background

NME5 Gene Knockout Cell Lines are genetically engineered cellular systems specifically designed to facilitate the study and manipulation of the NME5 gene’s function. By employing CRISPR/Cas9 technology, these cell lines provide a robust tool for researchers looking to delineate the biological roles and pathways influenced by NME5 in a variety of cellular contexts, including cancer biology and metabolic regulation.

The primary function of the NME5 Gene Knockout Cell Lines is to enable the investigation of gene expression, interaction networks, and phenotypic changes associated with the absence of the NME5 gene. Utilizing knockout techniques, these cell lines exhibit a complete loss of NME5 activity, allowing researchers to explore downstream signaling pathways and assess the gene's contribution to cellular behaviors, such as proliferation, differentiation, and apoptosis. This mechanistic insight can be invaluable for understanding disease mechanisms and developing targeted therapeutic strategies.

The scientific importance of NME5 Gene Knockout Cell Lines extends into both research and clinical settings. In research, these cell lines are pivotal for elucidating the role of NME5 in various diseases, laying the groundwork for future translational studies. Clinically, the insights gained from studying these knockouts could inform biomarker discovery and novel therapeutic approaches for conditions linked to the NME5 gene.

Among the unique advantages of our NME5 Gene Knockout Cell Lines is their precise genetic modification, which allows for high reproducibility and reliability in experimental results. Unlike alternative products that may not achieve complete knockout or lack validation, our cell lines undergo thorough quality control and characterization to ensure their effectiveness and stability. This reliability empowers researchers to obtain clearer, more consistent data, ultimately enhancing the productivity of their research efforts.

In summary, NME5 Gene Knockout Cell Lines represent a cutting-edge resource for both basic and applied research, providing critical insights into gene function and associated pathways. Our company prides itself on its commitment to quality and excellence in producing advanced biological products, providing researchers and clinicians with the tools necessary to drive impactful scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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