Gene: NKX3-1
Official Full Name: NK3 homeobox 1provided by HGNC
Gene Summary: This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jan 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36334 | NKX3-1 Knockout cell line (HeLa) | Human | NKX3-1 | 1:3~1:6 | Negative | Online Inquiry |
KO36335 | NKX3-1 Knockout cell line (HCT 116) | Human | NKX3-1 | 1:2~1:4 | Negative | Online Inquiry |
KO36336 | NKX3-1 Knockout cell line (HEK293) | Human | NKX3-1 | 1:3~1:6 | Negative | Online Inquiry |
KO36337 | NKX3-1 Knockout cell line (A549) | Human | NKX3-1 | 1:3~1:4 | Negative | Online Inquiry |
NKX3-1 Gene Knockout Cell Lines are precision-engineered cellular models created to facilitate the study of the NKX3-1 gene, a crucial transcription factor implicated in prostate development and oncogenesis. By utilizing advanced CRISPR/Cas9 gene-editing technologies, these cell lines are specifically designed to silence the expression of the NKX3-1 gene, allowing researchers to explore the molecular pathways influenced by this gene in both normal physiology and disease states.
The primary function of these knockout cell lines lies in their ability to emulate the loss-of-function effects associated with NKX3-1 deletion, providing insights into gene regulation, tumor progression, and the cellular microenvironment. Researchers can utilize these cells to investigate how the absence of NKX3-1 alters signaling cascades, gene expression profiles, and cellular behaviors, facilitating a deeper understanding of prostate cancer biology.
The scientific importance of NKX3-1 Gene Knockout Cell Lines is underscored by their applications in both basic research and preclinical studies. They serve as valuable tools for investigating potential therapeutic targets, examining disease mechanisms, and testing the efficacy of new treatments in a controlled environment, thereby contributing to the advancement of personalized medicine in urology.
Compared to existing alternative models, these specialized knockout cell lines offer superior specificity, reliability, and reproducibility, significantly enhancing experimental accuracy. The precise knockout of NKX3-1 ensures that findings are directly attributable to the gene's absence, reducing background noise often associated with other models.
For researchers and clinicians, the value of NKX3-1 Gene Knockout Cell Lines lies in their ability to provide high-quality, relevant data that can drive innovation in prostate cancer research. With a comprehensive understanding of this gene's role, users can uncover new insights that propel both therapeutic development and improved patient outcomes.
Our company brings decades of expertise in the creation of cutting-edge biological products, ensuring that these NKX3-1 Gene Knockout Cell Lines meet the highest standards of quality and performance. By choosing our products, researchers gain access to a robust resource that accelerates discovery and drives impactful scientific advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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