Home / NIT2 Knockout Cell Lines

NIT2 Knockout Cell Lines

Gene: NIT2

Official Full Name: nitrilase family member 2provided by HGNC

Gene Summary: Enables omega-amidase activity. Involved in asparagine metabolic process; glutamine metabolic process; and oxaloacetate metabolic process. Located in centrosome and cytosol. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20904 NIT2 Knockout cell line (HeLa) Human NIT2 1:3~1:6 Negative Online Inquiry
KO20905 NIT2 Knockout cell line (HCT 116) Human NIT2 1:2~1:4 Negative Online Inquiry
KO20906 NIT2 Knockout cell line (HEK293) Human NIT2 1:3~1:6 Negative Online Inquiry
KO20907 NIT2 Knockout cell line (A549) Human NIT2 1:3~1:4 Negative Online Inquiry

Background

NIT2 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to study the biological and functional impacts of the NIT2 gene, a critical component in glucose metabolism and insulin secretion pathways. By utilizing CRISPR-Cas9 technology, these cell lines have been meticulously developed to facilitate the investigation of gene function by creating precise deletions that eliminate the expression of the NIT2 gene.

The primary function of NIT2 Gene Knockout Cell Lines lies in their ability to enable researchers to dissect the role of the NIT2 gene within metabolic pathways. By observing cellular behavior post-knockout, scientists can determine the gene's contribution to processes such as glycolysis, gluconeogenesis, and cellular responses to insulin. This innovative approach allows for a clearer understanding of how variations in the NIT2 gene may be linked to metabolic disorders, including obesity and type 2 diabetes.

The scientific importance of these knockout cell lines extends into both research and clinical applications. They serve as a vital tool in pharmacological studies aimed at identifying potential therapeutic targets for metabolic diseases. Additionally, these cell lines can be utilized for high-throughput screening of small molecules, potentially leading to the development of novel drugs aimed at modulating NIT2 activity.

One of the unique selling points of NIT2 Gene Knockout Cell Lines is their specificity and reliability, which significantly outperform traditional methods such as RNA interference. Moreover, they provide reproducible results within controlled environments, which are essential for rigorous scientific investigations. The ease of use and adaptability of these cell lines, combined with robust protocols for maintenance and experimentation, further enhance their appeal to researchers.

For researchers and clinicians invested in metabolic research, NIT2 Gene Knockout Cell Lines represent a crucial resource that can expedite the discovery of innovative solutions to pressing health challenges. With a strong commitment to advancing scientific knowledge, our company brings unparalleled expertise in the development of sophisticated biological products, ensuring that our NIT2 Gene Knockout Cell Lines meet the highest standards of quality and efficacy for our valued customers.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.