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NIBAN2 Knockout Cell Lines

Gene: NIBAN2

Official Full Name: niban apoptosis regulator 2provided by HGNC

Gene Summary: Enables transcription coactivator activity. Involved in several processes, including gonadotropin secretion; negative regulation of apoptotic process; and regulation of nucleobase-containing compound metabolic process. Located in several cellular components, including adherens junction; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09260 NIBAN2 Knockout cell line (HeLa) Human NIBAN2 1:3~1:6 Negative Online Inquiry
KO09261 NIBAN2 Knockout cell line (HCT 116) Human NIBAN2 1:2~1:4 Negative Online Inquiry
KO09262 NIBAN2 Knockout cell line (HEK293) Human NIBAN2 1:3~1:6 Negative Online Inquiry
KO09263 NIBAN2 Knockout cell line (A549) Human NIBAN2 1:3~1:4 Negative Online Inquiry

Background

NIBAN2 Gene Knockout Cell Lines are a specialized tool for studying the role of the NIBAN2 gene in various biological processes. These cell lines have been engineered to contain precise deletions in the NIBAN2 gene, enabling researchers to elucidate its functions and assess its implications in cellular pathways, disease mechanisms, and therapeutic responses. The knockout mechanism is achieved through advanced CRISPR/Cas9 technology, which allows for a targeted disruption of the NIBAN2 gene, providing a robust model for functional studies.

The critical functions of NIBAN2 include its involvement in apoptosis, cell proliferation, and stress response, which are fundamental processes in maintaining cellular homeostasis and disease development. By examining these knockout cell lines, scientists can dissect the contributions of NIBAN2 to tumorigenesis, neurobiology, and immune response, ultimately enhancing our understanding of various pathological states.

In research settings, these knockout cell lines are invaluable tools for drug discovery, genetic screening, and functional genomics studies. Their application extends into clinical research, where insights gained may facilitate the identification of biomarkers for patient stratification and the development of targeted therapies. Furthermore, NIBAN2 knockout models can be employed to explore potential therapeutic avenues for conditions such as cancers and neurodegenerative diseases.

What sets NIBAN2 Gene Knockout Cell Lines apart from alternative models is their reliability and specificity. They offer researchers a controlled environment that mirrors native cellular behavior, minimizing off-target effects commonly seen with other genetic manipulation techniques. This ensures that observed phenotypic outcomes can be confidently attributed to the knockout of the NIBAN2 gene.

For researchers and clinicians seeking to deepen their understanding of NIBAN2's functional biology, these cell lines provide a crucial resource that can drive innovation and discovery. Our company boasts extensive expertise in genetic engineering and cell line development, ensuring that we deliver high-quality, ready-to-use models that empower researchers in their quest for scientific advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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