Gene: NHLRC1
Official Full Name: NHL repeat containing E3 ubiquitin protein ligase 1provided by HGNC
Gene Summary: The protein encoded by this gene is a single subunit E3 ubiquitin ligase. Laforin is polyubiquitinated by the encoded protein. Defects in this intronless gene lead to an accumulation of laforin and onset of Lafora disease, also known as progressive myoclonic epilepsy type 2 (EPM2).[provided by RefSeq, Mar 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15753 | NHLRC1 Knockout cell line (HeLa) | Human | NHLRC1 | 1:3~1:6 | Negative | Online Inquiry |
KO15754 | NHLRC1 Knockout cell line (HEK293) | Human | NHLRC1 | 1:3~1:6 | Negative | Online Inquiry |
KO15755 | NHLRC1 Knockout cell line (A549) | Human | NHLRC1 | 1:3~1:4 | Negative | Online Inquiry |
NHLRC1 Gene Knockout Cell Lines are a specialized tool designed for comprehensive in vitro studies, enabling researchers to investigate the biological functions and therapeutic potential associated with the NHLRC1 gene. This gene plays a pivotal role in various cellular processes, including apoptosis and immune response modulation. By utilizing these knockout cell lines, scientists can effectively disrupt the expression of NHLRC1 to observe resultant physiological changes, thus facilitating a deeper understanding of the gene's contribution to cellular dynamics and pathologies.
The key mechanism of action of these cell lines lies in their engineered loss-of-function characteristic. The knockout process is achieved through precise genomic editing techniques, such as CRISPR/Cas9, allowing researchers to create a model system that mimics certain disease states. This approach not only aids in elucidating the gene's function but also allows for the evaluation of potential therapeutic interventions aimed at correcting the dysfunctional cellular pathways that may arise from NHLRC1 aberrations.
In the realm of scientific research and clinical applications, NHLRC1 Gene Knockout Cell Lines are invaluable. They are instrumental in oncology, immunology, and neurology research, where understanding the role of NHLRC1 could lead to novel biomarker identification or targeted therapies for diseases like cancer and autoimmune disorders. Researchers rely on these models for high-throughput screening of drugs and understanding the underlying mechanisms of disease progression.
What sets our NHLRC1 Gene Knockout Cell Lines apart from alternative products is their high specificity and reproducibility, backed by robust validation processes. Unlike off-the-shelf solutions, our lines are developed under strict quality control, ensuring consistent performance across experiments. This gives researchers confidence in the data they generate, allowing for more reliable translational applications.
For researchers and clinicians, the value of NHLRC1 Gene Knockout Cell Lines is profound. They empower users to translate complex genetic mechanisms into actionable insights, potentially leading to significant breakthroughs in treatment strategies. Our company's commitment to advancing biological research through innovative solutions exemplifies our expertise in the field. We provide superior quality products that are designed to meet the evolving needs of the scientific community, ensuring researchers can achieve their objectives with confidence.
Please note that all services are for research use only. Not intended for any clinical use.
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