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NFIC Knockout Cell Lines

Gene: NFIC

Official Full Name: nuclear factor I Cprovided by HGNC

Gene Summary: The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36382 NFIC Knockout cell line (HeLa) Human NFIC 1:3~1:6 Negative Online Inquiry
KO36383 NFIC Knockout cell line (HCT 116) Human NFIC 1:2~1:4 Negative Online Inquiry
KO36384 NFIC Knockout cell line (HEK293) Human NFIC 1:3~1:6 Negative Online Inquiry
KO36385 NFIC Knockout cell line (A549) Human NFIC 1:3~1:4 Negative Online Inquiry

Background

NFIC Gene Knockout Cell Lines are engineered cellular models specifically designed to study the function of the NFIC gene, which plays a crucial role in various biological processes, including cell differentiation, proliferation, and response to stress. These cell lines have been generated through advanced CRISPR-Cas9 technology, creating precise deletions of the NFIC gene, thus allowing researchers to investigate the resultant phenotypic changes and molecular mechanisms directly attributable to the absence of NFIC expression.

The primary function of NFIC Gene Knockout Cell Lines is to facilitate in-depth exploration of NFIC’s role in various cellular pathways. When NFIC is knocked out, researchers can observe alterations in gene expression profiles, cellular signaling pathways, and metabolic shifts, leading to a better understanding of its role in diseases, such as cancer and metabolic syndrome. Crucially, these models enable high-throughput screening and functional studies that pinpoint therapeutic targets for drug development or precision medicine.

The scientific importance of NFIC Gene Knockout Cell Lines extends to both basic research and clinical applications. Their utilization in cancer research aids in elucidating NFIC's contributions to tumorigenesis, while investigations into metabolic disorders can reveal how NFIC influences glucose homeostasis and lipid metabolism. This dual applicability makes these cell lines versatile tools in both academic and industry settings.

Compared to traditional knockdown methods, NFIC Gene Knockout Cell Lines offer significant advantages, including permanent gene disruption, which leads to stable cell lines that maintain knockout characteristics over prolonged culture periods. Additionally, their well-characterized nature streamlines experimental designs, reducing variability and enhancing reproducibility in research outcomes.

Researchers and clinicians will find NFIC Gene Knockout Cell Lines invaluable for their ability to foster innovative discoveries and advance therapeutic strategies. These models provide a robust system for elucidating gene function and discovering new pathways, making them essential assets in molecular biology and translational research.

At our company, we pride ourselves on our commitment to quality and innovation, leveraging cutting-edge technologies to provide researchers with premier biological products. Our expertise in generating reliable gene knockout models ensures that our customers can confidently advance their scientific inquiries and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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