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NENF Knockout Cell Lines

Gene: NENF

Official Full Name: neudesin neurotrophic factorprovided by HGNC

Gene Summary: This gene encodes a neurotrophic factor that may play a role in neuron differentiation and development. A pseudogene of this gene is found on chromosome 12. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26925 NENF Knockout cell line (HeLa) Human NENF 1:3~1:6 Negative Online Inquiry
KO26926 NENF Knockout cell line (HCT 116) Human NENF 1:2~1:4 Negative Online Inquiry
KO26927 NENF Knockout cell line (HEK293) Human NENF 1:3~1:6 Negative Online Inquiry
KO26928 NENF Knockout cell line (A549) Human NENF 1:3~1:4 Negative Online Inquiry

Background

NENF Gene Knockout Cell Lines are uniquely engineered cell models specifically designed to investigate the functional role of the NENF gene, a critical component implicated in neurogenesis and synaptic plasticity. These knockout cell lines are generated using cutting-edge CRISPR-Cas9 gene editing technology to precisely disrupt the NENF gene, enabling researchers to study its absence and related biological pathways in various cellular contexts.

The key function of these cell lines lies in their ability to facilitate in-depth functional assays, providing insights into the gene's role in neuronal development and dysfunction. By using NENF knockout models, researchers can elucidate the mechanisms underlying neurodegenerative diseases, psychiatric disorders, and other conditions linked to synaptic transmission. This detailed examination is made possible through various applications such as transcriptomic and proteomic analyses, electrophysiological studies, and drug screening operations in a controlled cellular environment.

From a scientific perspective, the NENF Gene Knockout Cell Lines fill a critical gap in genetic research. Their application in clinical settings has the potential to accelerate the identification of novel therapeutic targets and the development of precision medicine strategies. Compared to traditional knockdown approaches, which may not completely eliminate gene function, these knockout cell lines offer a more reliable system for studying gene function and the effects of loss of function without the confounding variables commonly seen in partial knockdown methodologies.

Researchers and clinicians will find immense value in these cell lines as they enable reproducible results and a deep understanding of the NENF gene's biological implications. Furthermore, the ease of use and adaptability of these knockout models make them an indispensable tool for any molecular biology laboratory focused on neurobiology or translational research.

At our company, we leverage years of expertise in genetic engineering and cell line development to offer cutting-edge biological products like the NENF Gene Knockout Cell Lines, ensuring researchers have access to high-quality tools that enhance scientific discovery and clinical advancements.

Please note that all services are for research use only. Not intended for any clinical use.

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