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NELFCD Knockout Cell Lines

Gene: NELFCD

Official Full Name: negative elongation factor complex member C/Dprovided by HGNC

Gene Summary: The NELF complex of proteins interacts with the DSIF protein complex to repress transcriptional elongation by RNA polymerase II. The protein encoded by this gene is an essential part of the NELF complex. Alternative translation initiation site usage results in the formation of two isoforms with different N-termini. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22477 NELFCD Knockout cell line (HeLa) Human NELFCD 1:3~1:6 Negative Online Inquiry
KO22478 NELFCD Knockout cell line (HCT 116) Human NELFCD 1:2~1:4 Negative Online Inquiry
KO22479 NELFCD Knockout cell line (HEK293) Human NELFCD 1:3~1:6 Negative Online Inquiry
KO22480 NELFCD Knockout cell line (A549) Human NELFCD 1:3~1:4 Negative Online Inquiry

Background

NELFCD Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of the NELFCD gene and its associated biological pathways. This product allows researchers to explore the effects of eliminating NELFCD expression, providing critical insights into gene function, regulation, and the potential implications in various physiological and pathological contexts.

The key function of NELFCD Gene Knockout Cell Lines relies on their capability to enable the examination of gene knockdown consequences on cellular processes such as transcription regulation, cell cycle dynamics, and response to stress. By utilizing CRISPR-Cas9 technology or other gene-editing techniques, these cell lines exhibit a complete loss of NELFCD protein expression, allowing for a nuanced study of the gene’s role in RNA transcription dynamics, cellular growth, and differentiation pathways.

The scientific significance of these cell lines manifests in their applications within molecular biology, genetics, and drug discovery research. In clinical settings, they serve as valuable resources for investigating the NELFCD gene's potential links to diseases, such as cancer or neurodegenerative disorders, thus aiding in the identification of therapeutic targets.

What sets NELFCD Gene Knockout Cell Lines apart from alternatives is their rigorous characterization and validation processes, ensuring high specificity and reproducibility in experimental outcomes. Additionally, they are accompanied by comprehensive technical support, streamlining the research workflow and enhancing user experience.

Researchers and clinicians will find this product invaluable for elucidating gene functions, validating hypotheses in gene-related disease mechanisms, and advancing personalized medicine approaches. By incorporating these advanced models into their studies, users are equipped to generate impactful findings that could lead to breakthroughs in therapeutic developments.

Our company prides itself on a strong foundation in biotechnological innovation, offering a wide array of genetically engineered cell lines underpinned by a commitment to scientific excellence and user-oriented service.

Please note that all services are for research use only. Not intended for any clinical use.

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