Gene: NECAP2
Official Full Name: NECAP endocytosis associated 2provided by HGNC
Gene Summary: This gene likely encodes a member of the adaptin-ear-binding coat-associated protein family. Studies of a similar protein in rat suggest a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15780 | NECAP2 Knockout cell line (HeLa) | Human | NECAP2 | 1:3~1:6 | Negative | Online Inquiry |
KO15781 | NECAP2 Knockout cell line (HCT 116) | Human | NECAP2 | 1:2~1:4 | Negative | Online Inquiry |
KO15782 | NECAP2 Knockout cell line (HEK293) | Human | NECAP2 | 1:3~1:6 | Negative | Online Inquiry |
KO15783 | NECAP2 Knockout cell line (A549) | Human | NECAP2 | 1:3~1:4 | Negative | Online Inquiry |
NECAP2 Gene Knockout Cell Lines are genetically engineered cell lines that have undergone targeted gene disruption of the NECAP2 gene, which plays a significant role in various cellular processes such as endocytosis and cellular trafficking. The knockout of NECAP2 allows researchers to study the downstream effects of its absence and assess its impact on cellular functions, providing valuable insights into gene function and related pathways.
These cell lines utilize advanced CRISPR-Cas9 gene-editing technology to ensure precise and efficient knockout, thus enabling the examination of NECAP2's contributions to cellular dynamics in controlled experimental settings. By using NECAP2 Gene Knockout Cell Lines, researchers can investigate the roles of this gene in various biological contexts, including its involvement in disease models, which can lead to a deeper understanding of pathophysiology and potential therapeutic targets.
The scientific importance of NECAP2 Gene Knockout Cell Lines extends beyond basic research; they are highly applicable in the development of novel cancer therapies, drug discovery, and the study of genetic diseases. Their ability to create a cellular model mimicking specific genetic conditions makes them a powerful tool in translational research.
Compared to traditional methods of gene knockout, such as homologous recombination, the CRISPR-based approach used in these cell lines offers significantly higher efficiency, reduced off-target effects, and a quicker turn-around time. Furthermore, these cell lines come with detailed validation data and are designed for easy use in experimental protocols, making them essential for both novice and experienced researchers.
For researchers and clinicians, the availability of NECAP2 Gene Knockout Cell Lines opens the door to a wealth of experimental possibilities, enhancing the ability to dissect molecular pathways and ultimately translate findings into clinical applications. By providing high-quality biological products, we demonstrate our commitment to supporting the scientific community through state-of-the-art research tools that drive biomedical discovery and innovation. Our expertise in developing and supplying advanced cell lines is matched by our dedication to facilitating life-changing research.
Please note that all services are for research use only. Not intended for any clinical use.
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