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NDST2 Knockout Cell Lines

Gene: NDST2

Official Full Name: N-deacetylase and N-sulfotransferase 2provided by HGNC

Gene Summary: This gene encodes a member of the N-deacetylase/N-sulfotransferase subfamily of the sulfotransferase 1 proteins. The encoded enzyme has dual functions in processing glucosamine and heparin polymers, including N-deacetylation and N-sulfation. The encoded protein may be localized to the Golgi. [provided by RefSeq, Feb 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34103 NDST2 Knockout cell line (HeLa) Human NDST2 1:3~1:6 Negative Online Inquiry
KO34104 NDST2 Knockout cell line (HCT 116) Human NDST2 1:2~1:4 Negative Online Inquiry
KO34105 NDST2 Knockout cell line (HEK293) Human NDST2 1:3~1:6 Negative Online Inquiry
KO34106 NDST2 Knockout cell line (A549) Human NDST2 1:3~1:4 Negative Online Inquiry

Background

NDST2 Gene Knockout Cell Lines are engineered cellular models specifically developed to study the function of the NDST2 gene, which encodes an enzyme involved in the modification of heparan sulfate chains. This product is indispensable for researchers focusing on glycobiology and cellular signaling pathways. By knocking out the NDST2 gene, these cell lines provide a controlled environment to dissect the role of heparan sulfate in various physiological and pathological processes.

The main function of these cell lines lies in their ability to elucidate the consequences of NDST2 gene disruption. The knockout mechanism allows for the comprehensive study of altered cellular interactions and signaling cascades, particularly those linked to cell proliferation, differentiation, and migration. The robust cellular models facilitate investigations into diseases where heparan sulfate modifications are implicated, such as cancer and developmental disorders.

In terms of scientific importance, NDST2 Gene Knockout Cell Lines have vast applications in both research and clinical settings. They serve as pivotal tools for drug discovery, allowing scientists to screen therapeutic compounds that target pathways influenced by heparan sulfate dynamics. Additionally, these models represent a critical resource in understanding the molecular underpinnings of diseases, potentially leading to innovative therapeutic strategies.

One of the distinctive advantages of using NDST2 Gene Knockout Cell Lines is their tailored nature, which provides specific insights that non-targeted models cannot offer. Compared to conventional cell lines, these knockout models result in clearer experimental outcomes, enhancing reproducibility and validity in research findings.

For researchers and clinicians, the value of NDST2 Gene Knockout Cell Lines is evident in their ability to drive forward scientific understanding and therapeutic advancement. They offer a cost-effective and efficient platform for studying gene function and contribute significantly to bridging the gap between molecular biology and clinical applications.

With a commitment to providing high-quality biological products, our company harnesses extensive expertise in molecular biology and genetic engineering, ensuring that our NDST2 Gene Knockout Cell Lines are of unparalleled quality to support your research needs.

Please note that all services are for research use only. Not intended for any clinical use.

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