Gene: NDEL1
Official Full Name: nudE neurodevelopment protein 1 like 1provided by HGNC
Gene Summary: Enables identical protein binding activity. Involved in chromosome segregation; positive regulation of GTPase activity; and regulation of intracellular protein transport. Located in kinetochore. Biomarker of schizophrenia. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25721 | NDEL1 Knockout cell line (HeLa) | Human | NDEL1 | 1:3~1:6 | Negative | Online Inquiry |
KO25722 | NDEL1 Knockout cell line (HCT 116) | Human | NDEL1 | 1:2~1:4 | Negative | Online Inquiry |
KO25723 | NDEL1 Knockout cell line (HEK293) | Human | NDEL1 | 1:3~1:6 | Negative | Online Inquiry |
KO25724 | NDEL1 Knockout cell line (A549) | Human | NDEL1 | 1:3~1:4 | Negative | Online Inquiry |
NDEL1 Gene Knockout Cell Lines are specialized cell lines that have undergone precise genetic modification to inactivate the NDEL1 gene, a crucial component involved in neuronal development and cellular signaling. These cell lines serve as invaluable tools in biological research, allowing scientists to elucidate the specific functions and physiological roles of the NDEL1 protein within various cellular contexts.
The key function of the NDEL1 gene is linked to the regulation of microtubule dynamics, a critical process for maintaining the structural integrity of neurons and facilitating intracellular transport. By employing techniques such as CRISPR-Cas9 genome editing, NDEL1 knockout cell lines enable researchers to observe the consequences of NDEL1 deficiency on cell morphology, differentiation, and signaling pathways. This mechanistic approach provides invaluable insights into the molecular underpinnings of neurodevelopmental disorders and potential therapeutic targets.
The scientific importance of NDEL1 knockout cell lines is underscored by their versatility in both basic and applied research settings. They are particularly relevant for studies exploring the etiology of neurodegenerative diseases, as well as investigations into synaptic function and plasticity. Furthermore, these cell lines are also applicable in drug discovery, allowing for high-throughput screening of potential neuroprotective agents.
What sets our NDEL1 Gene Knockout Cell Lines apart from other alternatives is their robust validation and high performance, ensuring reproducibility and reliability in experimental outcomes. We employ comprehensive quality control measures and provide detailed characterization data, allowing users to confidently interpret their results. Our product is designed to accommodate a range of applications, making it ideal for both academic research institutions and pharmaceutical companies alike.
For researchers and clinicians striving to gain a deeper understanding of neurobiology, our NDEL1 Gene Knockout Cell Lines offer a unique opportunity to simplify complex experiments, enhance data quality, and accelerate discoveries. Backed by our company’s extensive expertise in developing cutting-edge biological reagents, we are committed to supporting the advancement of life sciences through innovative solutions that meet the highest scientific standards.
Please note that all services are for research use only. Not intended for any clinical use.
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