Gene: NCLN
Official Full Name: nicalinprovided by HGNC
Gene Summary: Enables ribosome binding activity. Involved in several processes, including multi-pass transmembrane protein insertion into ER membrane; protein stabilization; and regulation of protein complex stability. Located in endoplasmic reticulum membrane. Part of multi-pass translocon complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15826 | NCLN Knockout cell line (HeLa) | Human | NCLN | 1:3~1:6 | Negative | Online Inquiry |
KO15827 | NCLN Knockout cell line (HCT 116) | Human | NCLN | 1:2~1:4 | Negative | Online Inquiry |
KO15828 | NCLN Knockout cell line (HEK293) | Human | NCLN | 1:3~1:6 | Negative | Online Inquiry |
KO15829 | NCLN Knockout cell line (A549) | Human | NCLN | 1:3~1:4 | Negative | Online Inquiry |
NCLN Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to facilitate the functional analysis of the NCLN gene, which plays a crucial role in the regulation of cellular processes such as cell cycle progression and apoptosis. These knockout cell lines provide researchers with the ability to observe the effects of complete gene inactivation on cellular behavior, thereby enabling detailed functional studies of the NCLN gene's contributions to various physiological and pathological conditions.
The primary mechanism of these cell lines is rooted in CRISPR/Cas9 technology, which allows for precise editing of the genome. This mechanism not only ensures the complete deletion of the NCLN gene but also minimizes off-target effects, ensuring robust experimental outcomes. With these knockout cell lines, researchers can effectively model diseases linked to NCLN gene dysregulation, further elucidating its role in cancer biology, metabolic disorders, and developmental studies.
The scientific importance of NCLN Gene Knockout Cell Lines is underscored in both research and clinical settings, providing unprecedented insights into gene function and relevance to therapeutic targets. These cell lines serve as invaluable tools for drug screening, biomarker discovery, and pathway elucidation, allowing for advancements in personalized medicine and targeted therapies.
What sets our NCLN Gene Knockout Cell Lines apart from alternative products is our commitment to rigorous quality control, extensive validation, and user-friendly protocols, making it easier for researchers to adopt this innovative tool. Unlike other gene knockout models that may exhibit variability in expression levels or background noise, our lines consistently deliver reliable data that researchers can trust.
By utilizing our NCLN Gene Knockout Cell Lines, researchers and clinicians are empowered with a transformative tool that aids in understanding complex biological systems, leading to informed therapeutic development. As a leader in the field of genetic engineering and cell biology, our company boasts years of expertise in creating high-quality, precise biological products, ensuring that you have access to the best resources for your research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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