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NAXD Knockout Cell Lines

Gene: NAXD

Official Full Name: NAD(P)HX dehydrataseprovided by HGNC

Gene Summary: Enables ATP-dependent NAD(P)H-hydrate dehydratase activity. Predicted to be involved in metabolite repair. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15863 NAXD Knockout cell line (HeLa) Human NAXD 1:3~1:6 Negative Online Inquiry
KO15864 NAXD Knockout cell line (HCT 116) Human NAXD 1:2~1:4 Negative Online Inquiry
KO15865 NAXD Knockout cell line (HEK293) Human NAXD 1:3~1:6 Negative Online Inquiry
KO15866 NAXD Knockout cell line (A549) Human NAXD 1:3~1:4 Negative Online Inquiry

Background

NAXD Gene Knockout Cell Lines represent a sophisticated tool in molecular biology designed to facilitate in-depth studies of gene function and associated cellular processes. These cell lines are engineered to lack the NAXD gene, allowing researchers to explore its role in metabolic pathways and cellular responses under various conditions. By leveraging CRISPR/Cas9 technology, these knockout cell lines exhibit precision gene editing, which eliminates the NAXD gene while minimizing off-target effects, a common concern in genomic studies.

The primary function of NAXD knockout cell lines is to serve as a model for understanding the biochemical and physiological implications of the absence of the NAXD gene. Research indicates that NAXD is involved in the metabolism of NADPH, a crucial cofactor in various biochemical reactions. Consequently, experiments utilizing these cell lines enable scientists to dissect the downstream effects on cellular metabolism, oxidative stress response, and potential links to various diseases such as cancer and metabolic disorders.

In terms of scientific significance, NAXD knockout cell lines provide critical insights that can enhance our understanding of pathophysiological mechanisms and facilitate the development of targeted therapeutic interventions in clinical settings. Their application is particularly valuable in drug discovery and testing, as they help identify potential candidates that modulate NAXD-related pathways.

Compared to traditional knockout methods, the NAXD Gene Knockout Cell Lines offer higher efficiency, reproducibility, and specificity. Furthermore, they are readily available in various genetic backgrounds, which allow for comprehensive studies in different cellular contexts. The unique value proposition lies in their ability to provide consistent and relevant biological data to researchers and clinicians alike, ultimately accelerating the pace of discovery.

As a leader in innovative biological products, our company possesses extensive expertise in genetic engineering and cell line development. We are committed to empowering the scientific community by providing robust tools that enable groundbreaking research and foster advancements in health and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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