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NAPB Knockout Cell Lines

Gene: NAPB

Official Full Name: NSF attachment protein betaprovided by HGNC

Gene Summary: This gene encodes a member of the soluble N-ethyl-maleimide-sensitive fusion attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. This gene encodes the SNAP beta isoform which has been shown to be preferentially expressed in brain tissue. The encoded protein also interacts with the GluR2 α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor subunit C-terminus and may play a role as a chaperone in the molecular processing of the AMPA receptor. [provided by RefSeq, Mar 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15871 NAPB Knockout cell line (HeLa) Human NAPB 1:3~1:6 Negative Online Inquiry
KO15872 NAPB Knockout cell line (HCT 116) Human NAPB 1:2~1:4 Negative Online Inquiry
KO15873 NAPB Knockout cell line (HEK293) Human NAPB 1:3~1:6 Negative Online Inquiry
KO15874 NAPB Knockout cell line (A549) Human NAPB 1:3~1:4 Negative Online Inquiry

Background

NAPB Gene Knockout Cell Lines are engineered cellular models designed to facilitate the study of gene function by creating targeted disruptions within specific genes. These cell lines are generated using advanced CRISPR-Cas9 technology, allowing for precise editing of the genome and the creation of knockout models that are invaluable in elucidating the biological roles of genes in various cellular processes.

The primary function of NAPB Gene Knockout Cell Lines lies in their capacity to provide researchers with tools to examine gene expression, protein function, and the effect of gene loss on cellular behavior. By removing or inactivating genes of interest, researchers can investigate how these changes affect cellular pathways and processes such as proliferation, differentiation, or response to therapies. The mechanistic insights gleaned from these knockout models are critical for advancing our understanding of genetic contributions to diseases, thus propelling both basic research and translational medicine.

The scientific importance of NAPB Gene Knockout Cell Lines is underscored by their diverse applications across research and clinical settings. In cancer research, for example, these knockout models can be utilized to identify potential therapeutic targets by delineating the genes that drive tumorigenesis. In drug discovery, they serve as platforms for screening candidate compounds and understanding resistance mechanisms. Moreover, their utility extends to studies in neurobiology, immunology, and metabolic disorders, making them versatile tools for various fields.

Comparatively, NAPB Gene Knockout Cell Lines stand out due to their high efficiency, reproducibility, and the extensive validation performed to ensure the fidelity of gene knockout. Unlike other gene-editing products that may rely on transient methods or less precise techniques, NAPB ensures stable and heritable gene disruption, leading to more reliable experimental outcomes. Additionally, the comprehensive documentation of parent cell lines and knockout events allows researchers to easily interpret results and replicate studies.

For researchers and clinicians seeking to expand their understanding of gene function and disease mechanisms, NAPB Gene Knockout Cell Lines represent a powerful asset. By providing a robust platform for genetic investigation, these cell lines help bridge the gap between laboratory discoveries and real-world clinical applications.

With expertise in genetic tools and a commitment to advancing research capabilities, our company is dedicated to providing high-quality biological products that empower scientists to drive innovation and discovery in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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