Gene: NAP1L2
Official Full Name: nucleosome assembly protein 1 like 2provided by HGNC
Gene Summary: The protein encoded by this intronless gene is a member of the nucleosome assembly protein (NAP) family. The encoded protein represents a class of tissue-specific factors that interact with chromatin to regulate neuronal cell proliferation. [provided by RefSeq, Jan 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36464 | NAP1L2 Knockout cell line (A549) | Human | NAP1L2 | 1:3~1:4 | Negative | Online Inquiry |
NAP1L2 Gene Knockout Cell Lines are genetically engineered model systems that lack the expression of the NAP1L2 gene, which encodes a nucleosome assembly protein critical for chromatin dynamics and gene regulation. These knockout cell lines serve as invaluable tools for researchers investigating the role of NAP1L2 in cellular processes such as proliferation, differentiation, and DNA repair. By employing techniques such as CRISPR/Cas9 gene editing, these cell lines have been meticulously developed to facilitate in-depth analyses of the functional consequences of NAP1L2 deletion.
The core mechanism of these cell lines involves the introduced mutations that disrupt the coding sequence of the NAP1L2 gene, thereby allowing researchers to study the resultant phenotypic variations. This helps elucidate its contribution to chromatin structure and function, as well as its implications in diverse biological phenomena and disease models. Scientific investigations utilizing these knockout lines may encompass cancer research, developmental biology, and epigenetics, ultimately enhancing our understanding of gene regulation mechanisms underlying pathology and cellular behavior.
One of the standout advantages of NAP1L2 Gene Knockout Cell Lines is their specificity, which allows for targeted studies without the confounding effects of compensatory gene expression often seen in alternative models like RNA interference or transient knockdowns. These cell lines provide a stable and reproducible platform for experimentation, facilitating high-throughput screening and functional assays critical for drug discovery and therapeutic interventions.
For researchers and clinicians, utilizing NAP1L2 knockout models enables the dissection of complex biological pathways and the identification of potential biomarkers and therapeutic targets. With each line tailored for performance, these systems empower scientists to generate more accurate data and insights that can directly translate into clinical applications.
Our company specializes in the production of high-quality, customized genetic models, supported by a team of experts in molecular biology and genetics. Through our comprehensive portfolio of gene knockout products, we are committed to advancing the frontiers of biological research and enhancing experimental consistency across various scientific inquiries.
Please note that all services are for research use only. Not intended for any clinical use.
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