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MZF1 Knockout Cell Lines

Gene: MZF1

Official Full Name: myeloid zinc finger 1provided by HGNC

Gene Summary: Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein homodimerization activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09827 MZF1 Knockout cell line (HeLa) Human MZF1 1:3~1:6 Negative Online Inquiry
KO09828 MZF1 Knockout cell line (HCT 116) Human MZF1 1:2~1:4 Negative Online Inquiry
KO09829 MZF1 Knockout cell line (HEK293) Human MZF1 1:3~1:6 Negative Online Inquiry
KO09830 MZF1 Knockout cell line (A549) Human MZF1 1:3~1:4 Negative Online Inquiry

Background

MZF1 Gene Knockout Cell Lines are specialized cellular models in which the MZF1 gene has been precisely disrupted, a critical component for studying gene function and regulatory pathways. The MZF1 gene encodes a transcription factor that plays a significant role in hematopoiesis and immune response, making these knockout lines invaluable tools in both basic and applied research settings. By removing the MZF1 gene, researchers can elucidate its biological functions, assess its role in diseases, and explore potential therapeutic targets.

The primary function of the MZF1 Gene Knockout Cell Lines is to serve as a platform for examining the downstream effects of MZF1 loss on cellular behaviors, including proliferation, differentiation, and apoptosis. Mechanistically, these knockout lines allow scientists to dissect the transcriptional networks influenced by MZF1 and how its absence might lead to aberrant cellular pathways pertinent to enzyme function and immune responses.

The scientific importance of these knockout cell lines extends to various research fields, such as immunology, oncology, and regenerative medicine. They provide an experimental framework for investigating MZF1-related pathologies, validating genetic interactions, and testing novel therapeutic interventions. Clinically, insights gained from these models could lead to breakthroughs in understanding blood disorders and developing targeted gene therapies.

One of the unique selling points of MZF1 Gene Knockout Cell Lines is their high specificity and reproducibility, providing reliable data compared to other methods such as CRISPR or siRNA knockdown, which may result in off-target effects. Additionally, our knockout lines come with extensive characterization and validation data, ensuring that researchers can confidently apply them in their studies.

For researchers and clinicians, these cell lines represent an exceptional resource to unlock complex genetic interactions and disease mechanisms, ultimately steering their investigations towards meaningful clinical implications. By choosing MZF1 Gene Knockout Cell Lines, users gain access to a robust toolset engineered for precision research in cutting-edge biological studies.

Our company stands at the forefront of cellular and molecular biology innovations, proudly offering high-quality biological products that empower scientific discovery and enhance research efficacy.

Please note that all services are for research use only. Not intended for any clinical use.

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