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MYPN Knockout Cell Lines

Gene: MYPN

Official Full Name: myopalladinprovided by HGNC

Gene Summary: Striated muscle in vertebrates comprises large proteins which must be organized properly to contract efficiently. Z-lines in striated muscle are a sign of this organization, representing the ends of actin thin filaments, titin, nebulin or nebulette and accessory proteins required for structure and function. This gene encodes a protein which interacts with nebulin in skeletal muscle or nebulette in cardiac muscle and alpha-actinin. In addition, this gene product can interact with a protein with the I-band indicating it has a regulatory as well as structural function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24740 MYPN Knockout cell line (HeLa) Human MYPN 1:3~1:6 Negative Online Inquiry
KO24741 MYPN Knockout cell line (A549) Human MYPN 1:3~1:4 Negative Online Inquiry

Background

MYPN Gene Knockout Cell Lines are a specialized set of genetically modified cell lines designed for the targeted disruption of the MYPN gene, which encodes a protein critical in various cellular processes, including muscle development and function. By using CRISPR-Cas9 gene-editing technology, these cell lines enable researchers to create precise, stable, and reproducible knockout models, allowing for the investigation of MYPN's roles in both normal physiological and pathophysiological contexts.

Key functions of the MYPN gene knockout cell lines include the ability to elucidate the mechanistic pathways influenced by the MYPN protein. Researchers can employ these knockout lines to assess cellular responses to various stimuli, study downstream signaling pathways, and examine the functional consequences of MYPN loss, particularly in conditions related to cardiac and skeletal muscle disorders. The precise gene editing provided by these knockout lines ensures a high level of specificity, minimizing off-target effects and enhancing the accuracy of experimental results.

The scientific importance of MYPN gene knockout cell lines is manifold, with applications spanning fundamental biological research, drug discovery, and therapeutic development. They are invaluable in studying genetic diseases and muscle dysfunction, providing insights that could lead to innovative intervention strategies for conditions such as cardiomyopathy.

Compared to conventional models, such as transgenic mice or unmodified cell lines, MYPN gene knockout cell lines offer several advantages, including ease of use, reduced time for establishment, and the potential for high-throughput applications. These cell lines facilitate complex experiments with greater reproducibility and less animal usage, addressing ethical considerations in research.

For researchers and clinicians seeking to deepen their understanding of genetic contributions to muscle biology, the MYPN Gene Knockout Cell Lines represent a powerful tool. Their precise knockout capabilities position scientists at the frontier of genetic research, paving the way for breakthroughs in therapeutic interventions.

Our company specializes in delivering high-quality biological products, and we ensure that our MYPN Gene Knockout Cell Lines meet rigorous standards for purity and characterization, empowering researchers with reliable tools for their critical investigations.

Please note that all services are for research use only. Not intended for any clinical use.

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