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MYO5B Knockout Cell Lines

Gene: MYO5B

Official Full Name: myosin VBprovided by HGNC

Gene Summary: The protein encoded by this gene, together with other proteins, may be involved in plasma membrane recycling. Mutations in this gene are associated with microvillous inclusion disease. [provided by RefSeq, Sep 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36484 MYO5B Knockout cell line (HeLa) Human MYO5B 1:3~1:6 Negative Online Inquiry
KO36485 MYO5B Knockout cell line (HCT 116) Human MYO5B 1:2~1:4 Negative Online Inquiry
KO36486 MYO5B Knockout cell line (HEK293) Human MYO5B 1:3~1:6 Negative Online Inquiry
KO36487 MYO5B Knockout cell line (A549) Human MYO5B 1:3~1:4 Negative Online Inquiry

Background

MYO5B Gene Knockout Cell Lines are innovative biological tools engineered to silence the MYO5B gene, which encodes for the motor protein Myosin Vb. This protein is essential for various intracellular transport processes, particularly in the trafficking of organelles and vesicles. By generating knockout cell lines, researchers can effectively study the functional implications of MYO5B loss, including its role in cellular dynamics, endocytosis, and exocytosis.

These cell lines operate through targeted gene editing techniques, such as CRISPR/Cas9, which introduces specific mutations leading to the gene's inactivation. This mechanism allows for a precise investigation into MYO5B's involvement in cellular pathways and disease models, making it instrumental for cutting-edge research in cell biology, neurobiology, and developmental biology.

The scientific importance of MYO5B Gene Knockout Cell Lines stems from their application in elucidating the molecular mechanisms underlying various disorders, such as neurological syndromes and epithelial cell dysfunctions. Researchers can utilize these models to explore therapeutic targets, understand pathophysiological processes, and develop potential interventions, thus positioning the cell lines as valuable assets in both academic and clinical laboratories.

Compared to alternative models, such as RNA interference or overexpression systems, knockout cell lines provide a more definitive approach to studying gene function by eliminating gene expression entirely, avoiding the partial knockdowns that may still yield residual activity. This specificity enhances the reliability of experimental outcomes.

For researchers and clinicians committed to advancing their understanding of gene function and disease mechanisms, MYO5B Gene Knockout Cell Lines offer unparalleled value. They not only facilitate high-throughput screening applications but also promote the discovery of novel therapeutic strategies by providing insights that stem from a complete loss-of-function scenario.

As an industry leader in genetic engineering and cellular research tools, our company is dedicated to providing high-quality, reliable products designed to empower the scientific community in their explorations of genetic and molecular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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