Gene: MYL5
Official Full Name: myosin light chain 5provided by HGNC
Gene Summary: This gene encodes one of the myosin light chains, a component of the hexameric ATPase cellular motor protein myosin. Myosin is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene product, one of the regulatory light chains, is expressed in fetal muscle and in adult retina, cerebellum, and basal ganglia. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36496 | MYL5 Knockout cell line (HeLa) | Human | MYL5 | 1:3~1:6 | Negative | Online Inquiry |
KO36497 | MYL5 Knockout cell line (HCT 116) | Human | MYL5 | 1:2~1:4 | Negative | Online Inquiry |
KO36498 | MYL5 Knockout cell line (HEK293) | Human | MYL5 | 1:3~1:6 | Negative | Online Inquiry |
KO36499 | MYL5 Knockout cell line (A549) | Human | MYL5 | 1:3~1:4 | Negative | Online Inquiry |
MYL5 Gene Knockout Cell Lines are genetically modified cell systems created for the precise study of the MYL5 gene, which encodes a protein critical for muscle function and contraction. By employing advanced CRISPR-Cas9 genome editing technology, these cell lines have been engineered to effectively eliminate the expression of MYL5, allowing researchers to investigate the role of this gene in muscle development and related pathologies.
The primary function of MYL5 Knockout Cell Lines is to serve as a valuable tool for understanding myofibrillogenesis and muscle physiology. By utilizing these cell lines, researchers can observe the cellular and molecular alterations that arise from the absence of the MYL5 protein, thereby elucidating pathways implicated in muscle disorders, including cardiomyopathies and muscular dystrophies. Moreover, these knockout lines enable the evaluation of potential therapeutic targets through high-throughput drug screening or gene reconstitution experiments.
The scientific significance of MYL5 Gene Knockout Cell Lines is profound, as they provide a model to explore muscle-related diseases at a cellular level, contributing invaluable knowledge to both basic and translational research. In a clinical context, findings derived from these cell lines have the potential to inform gene therapy approaches, therapeutic interventions, and drug development tailored to muscle dysfunction.
Compared to traditional cell lines that express the MYL5 gene, these knockout lines offer a unique advantage by allowing for a precise dissection of MYL5's contributions to muscle biology without confounding factors. This makes them especially beneficial for researchers focused on muscle genetics and signaling pathways.
For researchers and clinicians alike, MYL5 Gene Knockout Cell Lines represent an essential resource in the quest to better understand muscular diseases, identify novel therapeutic strategies, and advance the field of muscle biology. Our company specializes in the development and production of high-quality biological products. With our expertise in genetic engineering and commitment to scientific innovation, we strive to equip researchers with the tools necessary to make groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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