Gene: MYL11
Official Full Name: myosin light chain 11provided by HGNC
Gene Summary: Predicted to enable calcium ion binding activity. Predicted to be a structural constituent of muscle. Involved in muscle contraction. Located in lysosomal membrane. Implicated in distal arthrogryposis type 1C. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15952 | MYL11 Knockout cell line (HeLa) | Human | MYL11 | 1:3~1:6 | Negative | Online Inquiry |
KO15953 | MYL11 Knockout cell line (HEK293) | Human | MYL11 | 1:3~1:6 | Negative | Online Inquiry |
MYL11 Gene Knockout Cell Lines are expertly engineered cellular models designed for the precise study of the MYL11 gene, which encodes the essential myosin light chain 11 protein. This product utilizes advanced CRISPR-Cas9 gene editing technology to create targeted deletions of the MYL11 gene, offering researchers a powerful tool for dissecting the gene's contribution to cardiac and smooth muscle function. By knocking out this gene, researchers can investigate the downstream effects on cellular signaling pathways and muscle contractility, allowing for a deeper understanding of diseases such as heart failure and hypertension.
The key mechanism behind these knockout cell lines involves the introduction of specific guide RNAs that direct the CRISPR-Cas9 system to the MYL11 gene, leading to precise genomic modifications. As a result, these cell lines provide a valuable resource for exploring gene function, validating drug targets, and screening potential therapeutics in both in vitro and in vivo models.
In research and clinical settings, MYL11 Gene Knockout Cell Lines serve as a critical platform for elucidating the pathophysiology of cardiovascular diseases. Their availability allows researchers to conduct targeted functional studies and to anticipate how variations in the MYL11 gene may influence muscle contraction dynamics and cardiac health. Compared to traditional methods of gene silencing, such as siRNA or shRNA, these knockout cell lines offer a more permanent and reversible option that can yield cleaner results and longer-term studies.
The unique selling points of MYL11 Gene Knockout Cell Lines include their specificity, reliability, and the reproducibility of results, making them an invaluable addition to any laboratory focused on muscle biology or cardiovascular research. By providing researchers and clinicians with verified, high-quality cell lines, we facilitate groundbreaking discoveries that could revolutionize therapeutic approaches to cardiac disorders.
Our company, with extensive expertise in genetic engineering and cell line development, is committed to delivering innovative biological products that empower scientific research and foster advancements in clinical practice. With MYL11 Gene Knockout Cell Lines, we offer a robust and dependable platform for exploring the complexities of gene function within muscle pathology.
Please note that all services are for research use only. Not intended for any clinical use.
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