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MYCBP2 Knockout Cell Lines

Gene: MYCBP2

Official Full Name: MYC binding protein 2provided by HGNC

Gene Summary: This gene encodes an E3 ubiquitin-protein ligase and member of the PHR (Phr1/MYCBP2, highwire and RPM-1) family of proteins. The encoded protein plays a role in axon guidance and synapse formation in the developing nervous system. In mammalian cells, this protein regulates the cAMP and mTOR signaling pathways, and may additionally regulate autophagy. Reduced expression of this gene has been observed in acute lymphoblastic leukemia patients and a mutation in this gene has been identified in patients with a rare inherited vision defect. [provided by RefSeq, Mar 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29902 MYCBP2 Knockout cell line (HeLa) Human MYCBP2 1:3~1:6 Negative Online Inquiry
KO29903 MYCBP2 Knockout cell line (HCT 116) Human MYCBP2 1:2~1:4 Negative Online Inquiry
KO29904 MYCBP2 Knockout cell line (HEK293) Human MYCBP2 1:3~1:6 Negative Online Inquiry
KO29905 MYCBP2 Knockout cell line (A549) Human MYCBP2 1:3~1:4 Negative Online Inquiry

Background

MYCBP2 Gene Knockout Cell Lines represent a powerful and innovative tool for studying gene function and the role of MYCBP2 (MYC Binding Protein 2) in cellular processes. These cell lines are genetically engineered to disrupt the MYCBP2 gene, creating a knockout model that allows researchers to investigate the physiological and pathological implications of MYCBP2 dysregulation in various biological contexts.

The primary function of MYCBP2 is to interact with and regulate the MYC oncogene, which is critical for cell growth, proliferation, and differentiation. By utilizing these knockout cell lines, scientists can elucidate the downstream signaling pathways affected by the absence of MYCBP2, thereby gaining insight into mechanisms of tumorigenesis, metabolic regulation, and cellular stress responses. This provides a foundational understanding that can lead to novel therapeutic targets and intervention strategies.

In research and clinical settings, MYCBP2 Gene Knockout Cell Lines are indispensable for accelerating drug discovery and developing targeted therapies for cancers associated with aberrant MYC signaling. Compared to traditional cell models, these knockout lines enable precise genetic manipulation, allowing for clearer interpretations of experimental outcomes and reducing confounding factors related to compensatory gene expression.

The unique selling point of MYCBP2 Gene Knockout Cell Lines lies in their specificity and robustness, offering researchers reliable data on gene function without the variability associated with other models. Their application spans academic research, biopharmaceutical development, and clinical diagnostics, positioning them as a versatile asset in the scientific toolkit.

For researchers and clinicians, investing in MYCBP2 Gene Knockout Cell Lines translates to a streamlined approach in elucidating disease mechanisms and accelerating the path to therapeutic advancements. Our company, with its dedicated expertise in genetic engineering and cell line development, is committed to providing high-quality biological products that empower innovators in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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