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MX1 Knockout Cell Lines

Gene: MX1

Official Full Name: MX dynamin like GTPase 1provided by HGNC

Gene Summary: This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01643 MX1 Knockout cell line (HeLa) Human MX1 1:3~1:6 Negative Online Inquiry

Background

MX1 Gene Knockout Cell Lines are specialized cellular models in which the MX1 gene has been systematically disrupted or “knocked out” through gene-editing technologies such as CRISPR/Cas9. The MX1 gene is crucial for the antiviral response, playing a significant role in the innate immune system's ability to combat viral infections. By employing these knockout cell lines, researchers can study the precise function of the MX1 gene, elucidate its mechanism in host-pathogen interactions, and gain a deeper understanding of cellular responses to viral pathogens.

The core functionality of the MX1 Gene Knockout Cell Lines lies in their ability to mimic the absence of MX1, providing a unique platform for investigating the pathways involved in immune response modulation. This can facilitate the examination of how viral infections exploit host cellular mechanisms and can be instrumental in assessing the efficacy of antiviral compounds. Additionally, these knockout models serve as valuable tools in the pharmaceutical development pipeline, enabling the identification of potential therapeutic targets and the evaluation of drug efficacy.

The scientific importance of MX1 Gene Knockout Cell Lines extends to their applications in both research and clinical settings. In virology, they offer insights into viral replication and pathogenesis, while in immunology, they allow for the evaluation of therapeutic strategies aimed at enhancing antiviral defenses. Researchers can utilize these cell lines to develop novel vaccines and treatments with heightened precision.

When compared to traditional cell lines that may not reflect the absence of specific genes, MX1 Gene Knockout Cell Lines provide a clean and defined experimental model that minimizes confounding factors. This specificity enhances reproducibility and reliability in experimental outcomes, making them an ideal choice for advanced research applications.

For researchers, clinicians, and pharmaceutical developers, investing in MX1 Gene Knockout Cell Lines not only expedites the exploration of antiviral mechanisms but also strengthens the foundation for future therapeutic interventions. Our company prides itself on delivering high-quality biological products backed by extensive scientific expertise, ensuring that each product meets the rigorous demands of cutting-edge research. With our MX1 Gene Knockout Cell Lines, you are equipped with a powerful tool that enables transformative discoveries in molecular biology and immunology.

Please note that all services are for research use only. Not intended for any clinical use.

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