Gene: MTSS2
Official Full Name: MTSS I-BAR domain containing 2provided by HGNC
Gene Summary: Enables GTPase activator activity and small GTPase binding activity. Involved in activation of GTPase activity and cellular response to platelet-derived growth factor stimulus. Located in ruffle membrane. Implicated in intellectual developmental disorder with ocular anomalies and distinctive facial features. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23244 | MTSS2 Knockout cell line (HeLa) | Human | MTSS2 | 1:3~1:6 | Negative | Online Inquiry |
KO23245 | MTSS2 Knockout cell line (HCT 116) | Human | MTSS2 | 1:2~1:4 | Negative | Online Inquiry |
KO23246 | MTSS2 Knockout cell line (HEK293) | Human | MTSS2 | 1:3~1:6 | Negative | Online Inquiry |
KO23247 | MTSS2 Knockout cell line (A549) | Human | MTSS2 | 1:3~1:4 | Negative | Online Inquiry |
MTSS2 Gene Knockout Cell Lines are specialized cell lines engineered to lack the expression of the MTSS2 gene, which encodes the metastasis suppressor protein T-plastin. These cell lines are vital tools for investigating the functional role of MTSS2 in cellular processes such as migration, adhesion, and invasion, particularly in the context of cancer metastasis. By utilizing CRISPR-Cas9 technology, our product ensures precise and efficient gene editing, resulting in robust and reproducible knockout models conducive to detailed study.
The key function of these knockout cell lines is to provide a platform for assessing the biological implications of MTSS2 deficiency. Studies have demonstrated that the loss of MTSS2 can significantly alter cellular behaviors that contribute to tumor progression and metastasis. Investigators can utilize these cell lines to explore pathways influenced by MTSS2, gaining insights into the molecular mechanisms that underscore cancer biology and potential therapeutic avenues.
From a scientific perspective, MTSS2 Gene Knockout Cell Lines serve as critical resources in both basic and applied research fields. These cell lines are expedient for use in functional assays, drug response studies, and the development of novel therapeutic strategies aimed at targeting cancer metastasis. They provide a streamlined model for examining the consequences of MTSS2 loss, offering a distinct advantage over non-targeted approaches.
Compared to alternatives such as wild-type or overexpression models, the specificity of knockout lines enables clearer delineation of gene function without the confounding influence of gene variants or compensatory pathways. Researchers and clinicians will appreciate the reliability and versatility of these cell lines, which can be seamlessly integrated into a wide variety of experimental paradigms.
Our commitment to fostering innovative biological solutions is exemplified through the high-quality development of these MTSS2 Gene Knockout Cell Lines. With expertise in genetic engineering and a focus on advancing cancer research, our company stands at the forefront of providing exceptional products that empower scientists and clinicians in their quest to unravel the complexities of disease.
Please note that all services are for research use only. Not intended for any clinical use.
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