Gene: MTFR2
Official Full Name: mitochondrial fission regulator 2provided by HGNC
Gene Summary: Predicted to be involved in aerobic respiration and mitochondrial fission. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30877 | MTFR2 Knockout cell line (HeLa) | Human | MTFR2 | 1:3~1:6 | Negative | Online Inquiry |
KO30878 | MTFR2 Knockout cell line (HCT 116) | Human | MTFR2 | 1:2~1:4 | Negative | Online Inquiry |
KO30879 | MTFR2 Knockout cell line (HEK293) | Human | MTFR2 | 1:3~1:6 | Negative | Online Inquiry |
KO30880 | MTFR2 Knockout cell line (A549) | Human | MTFR2 | 1:3~1:4 | Negative | Online Inquiry |
MTFR2 Gene Knockout Cell Lines are specialized cellular models that have been genetically engineered to lack the activity of the MTFR2 gene, which is implicated in mitochondrial function and cellular metabolism. These cell lines serve as invaluable tools in scientific research, particularly in the fields of oncology, neurology, and metabolic disorders. By creating a deliberate disruption in the MTFR2 gene, researchers can study the downstream effects on mitochondrial dynamics and cellular physiology, providing insights into how alterations in this gene contribute to various pathologies.
The primary function of MTFR2 Gene Knockout Cell Lines is to enable the study of mitochondrial biogenesis, dynamics, and their role in disease mechanisms. The absence of the MTFR2 gene allows for the observation of mitochondrial-related processes, such as respiration and reactive oxygen species (ROS) generation, under controlled conditions. This offers an effective approach to identify potential therapeutic targets and unravel the complexities of mitochondrial biology.
In research and clinical settings, these cell lines are crucial for understanding diseases characterized by mitochondrial dysfunction, including neurodegenerative diseases and certain cancers. They facilitate high-throughput screening of pharmacological agents or genetic interventions aimed at restoring normal mitochondrial function, thereby highlighting their potential in drug development and personalized medicine.
Compared to other knockout models, MTFR2 Gene Knockout Cell Lines are uniquely valuable due to their specific focus on mitochondrial pathways, which are often overlooked in broader genetic studies. This specialization allows for more precise hypotheses and experimental designs centered around mitochondrial health and metabolic regulation.
For researchers and clinicians looking to deepen their understanding of mitochondrial function or explore therapeutic interventions, MTFR2 Gene Knockout Cell Lines offer an essential resource. Their robustness, coupled with the capability to reveal intricate cellular mechanisms, makes them an indispensable asset in biological research.
Our company specializes in developing high-quality genetic models to meet the evolving needs of the scientific community, ensuring that our products facilitate groundbreaking discoveries in biology and medicine.
Please note that all services are for research use only. Not intended for any clinical use.
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