Gene: MTFR1
Official Full Name: mitochondrial fission regulator 1provided by HGNC
Gene Summary: This gene encodes a mitochondrial protein that is characterized by a poly-proline rich region. A chicken homolog of this protein promotes mitochondrial fission and the mouse homolog protects cells from oxidative stress. A related pseudogene of this gene is found on chromosome X. [provided by RefSeq, Mar 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32977 | MTFR1 Knockout cell line (HeLa) | Human | MTFR1 | 1:3~1:6 | Negative | Online Inquiry |
KO32978 | MTFR1 Knockout cell line (HCT 116) | Human | MTFR1 | 1:2~1:4 | Negative | Online Inquiry |
KO32979 | MTFR1 Knockout cell line (HEK293) | Human | MTFR1 | 1:3~1:6 | Negative | Online Inquiry |
KO32980 | MTFR1 Knockout cell line (A549) | Human | MTFR1 | 1:3~1:4 | Negative | Online Inquiry |
MTFR1 Gene Knockout Cell Lines are specialized cell line models that have been engineered to lack the expression of the MTFR1 gene, implicated in critical cellular processes such as mitochondrial dynamics and cellular response to stress. This knockout is achieved using advanced genetic editing technologies, enabling researchers to elucidate the role of MTFR1 in various physiological and pathological contexts.
The primary functions of the MTFR1 Gene Knockout Cell Lines include enabling the study of mitochondrial function, apoptosis, and cellular metabolism. By observing the phenotypic and biochemical changes that occur in the absence of MTFR1, researchers can gain insights into its role in conditions such as neurodegenerative diseases, cancer, and metabolic disorders. The mechanisms underlying mitochondrial morphology changes and energy production pathways can be more clearly understood, paving the way for new therapeutic strategies.
Scientifically, these knockout cell lines are invaluable in both research and clinical settings. They serve as crucial tools for deciphering the MTFR1-mediated regulatory networks that control cellular health and disease states. Their application extends to drug discovery and testing, where understanding gene function is pivotal for developing targeted therapies.
The unique selling point of the MTFR1 Gene Knockout Cell Lines lies in their precision and reliability compared to existing models. As these lines are developed with cutting-edge CRISPR/Cas9 technology, they offer a complete ablation of the target gene, minimizing off-target effects that can confound experimental results. Furthermore, they are rigorously validated for consistency in growth and behavior, ensuring researchers obtain reproducible and accurate data.
For researchers and clinicians, the value of the MTFR1 Gene Knockout Cell Lines is clear: they provide a robust platform for investigating the fundamental biology of mitochondrial function and disease mechanisms, creating opportunities for innovation in therapeutic development. Backed by our company's extensive expertise in genetic engineering and cell line development, we are committed to providing high-quality biological products that advance scientific discovery and improve human health.
Please note that all services are for research use only. Not intended for any clinical use.
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