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MTARC2 Knockout Cell Lines

Gene: MTARC2

Official Full Name: mitochondrial amidoxime reducing component 2provided by HGNC

Gene Summary: The protein encoded by this gene is an enzyme found in the outer mitochondrial membrane that reduces N-hydroxylated substrates. The encoded protein uses molybdenum as a cofactor and cytochrome b5 type B and NADH cytochrome b5 reductase as accessory proteins. One type of substrate used is N-hydroxylated nucleotide base analogues, which can be toxic to a cell. Other substrates include N(omega)-hydroxy-L-arginine (NOHA) and amidoxime prodrugs, which are activated by the encoded enzyme. Multiple transcript variants encoding the different isoforms have been found for this gene. [provided by RefSeq, Sep 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15985 MTARC2 Knockout cell line (HeLa) Human MTARC2 1:3~1:6 Negative Online Inquiry
KO15986 MTARC2 Knockout cell line (HCT 116) Human MTARC2 1:2~1:4 Negative Online Inquiry
KO15987 MTARC2 Knockout cell line (HEK293) Human MTARC2 1:3~1:6 Negative Online Inquiry
KO15988 MTARC2 Knockout cell line (A549) Human MTARC2 1:3~1:4 Negative Online Inquiry

Background

MTARC2 Gene Knockout Cell Lines are highly specialized biological tools that provide researchers with the ability to study the function of the MTARC2 gene by enabling its specific inactivation within a cellular context. These cell lines are meticulously engineered using CRISPR/Cas9 technology, which allows for precise genomic editing and the generation of knockout models that can facilitate the exploration of gene function, related signaling pathways, and phenotypic responses in various biological systems.

One of the key functions of MTARC2 Gene Knockout Cell Lines is their role in elucidating the gene's contribution to metabolic regulation and mitochondrial dynamics. By creating these knockout models, researchers can assess alterations in cellular metabolism, energy production, and overall cell viability, providing insights that can lead to advancements in understanding diseases such as cancer and metabolic disorders. Moreover, the ability to utilize these cell lines in high-throughput screening enables efficient drug discovery and validation processes, paving the way for novel therapeutic approaches.

The scientific importance of our MTARC2 Gene Knockout Cell Lines extends beyond basic research; they have critical applications in both preclinical studies and clinical research settings. These cell lines serve as a benchmark for pharmacological studies and can be instrumental in the development of targeted therapies aimed at modulating the pathways influenced by MTARC2.

Unlike conventional knockout models, which may involve lengthy and cumbersome processes, our MTARC2 Gene Knockout Cell Lines offer a rapid and reliable approach to genetic studies, significantly reducing time and resources required for experimentation. This capability is further enhanced by the consistent performance and reproducibility of these cell lines, ensuring that researchers can obtain reliable results that are vital for their studies.

For researchers and clinicians seeking to advance their understanding of gene function and disease mechanisms, the MTARC2 Gene Knockout Cell Lines represent a valuable asset. By streamlining experimental workflows and delivering precise, on-target gene modifications, these cell lines empower users to unlock new avenues of research.

Our company specializes in providing high-quality biological products tailored to the needs of the scientific community. With a commitment to innovation and excellence, we offer a wide range of advanced tools designed to enhance research efficacy and foster breakthroughs in therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

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