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MSMB Knockout Cell Lines

Gene: MSMB

Official Full Name: microseminoprotein betaprovided by HGNC

Gene Summary: The protein encoded by this gene is a member of the immunoglobulin binding factor family. It is synthesized by the epithelial cells of the prostate gland and secreted into the seminal plasma. This protein has inhibin-like activity. It may have a role as an autocrine paracrine factor in uterine, breast and other female reproductive tissues. The expression of the encoded protein is found to be decreased in prostate cancer. Two alternatively spliced transcript variants encoding different isoforms are described for this gene. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36549 MSMB Knockout cell line (HeLa) Human MSMB 1:3~1:6 Negative Online Inquiry

Background

MSMB Gene Knockout Cell Lines are biologically engineered cellular models specifically designed to elucidate the functional roles of the MSMB gene, which is implicated in various physiological and pathological processes, including prostate cancer progression. By employing CRISPR-Cas9 technology, these cell lines exhibit a complete knockout of MSMB, allowing for in-depth studies of gene function and the associated biological pathways.

The key mechanism by which MSMB Gene Knockout Cell Lines operate is through the targeted disruption of the MSMB gene, leading to a loss of its protein product. This absence enables researchers to investigate gene expression profiles, cellular behavior changes, and the downstream effects on signaling pathways involved in cell proliferation, apoptosis, and metastasis. Consequently, these mutant cell lines serve as invaluable tools in the assessment of therapeutic interventions, biomarker discovery, and the understanding of tumor microenvironment interactions.

The scientific importance of these knockout cell lines extends into both research and clinical settings. They are essential for dissecting the molecular mechanisms of diseases related to MSMB, thus providing pivotal insights that can drive drug development and guide clinical decision-making. Compared to traditional cell line models, MSMB Gene Knockout Cell Lines offer a more precise and reliable means of modeling the gene’s role, significantly enhancing the accuracy of experimental outcomes.

Distinguished by their robust genetic validation and reproducibility, these cell lines provide researchers and clinicians with unique advantages, such as accelerated timelines for experimental setup and potential to uncover novel therapeutic targets. Furthermore, their ease of use and compatibility with various assays make them a preferred choice for studies aimed at both basic and translational research.

By choosing MSMB Gene Knockout Cell Lines, you align with a company that is committed to advancing biotechnological applications through its state-of-the-art cell line offerings. We pride ourselves on delivering high-quality products backed by rigorous scientific research, ensuring you have the tools necessary to propel your investigations forward.

Please note that all services are for research use only. Not intended for any clinical use.

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