Gene: MSI2
Official Full Name: musashi RNA binding protein 2provided by HGNC
Gene Summary: This gene encodes an RNA-binding protein that is a member of the Musashi protein family. The encoded protein is transcriptional regulator that targets genes involved in development and cell cycle regulation. Mutations in this gene are associated with poor prognosis in certain types of cancers. This gene has also been shown to be rearranged in certain cancer cells. [provided by RefSeq, Apr 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04312 | MSI2 Knockout cell line (HeLa) | Human | MSI2 | 1:3~1:6 | Negative | Online Inquiry |
KO04313 | MSI2 Knockout cell line (HCT 116) | Human | MSI2 | 1:2~1:4 | Negative | Online Inquiry |
KO04314 | MSI2 Knockout cell line (HEK293) | Human | MSI2 | 1:3~1:6 | Negative | Online Inquiry |
KO04315 | MSI2 Knockout cell line (A549) | Human | MSI2 | 1:3~1:4 | Negative | Online Inquiry |
MSI2 Gene Knockout Cell Lines are specialized cellular models in which the MSI2 gene has been effectively disrupted through the CRISPR-Cas9 gene-editing technology. MSI2, or Musashi RNA-binding protein 2, is known for its pivotal role in post-transcriptional gene regulation, and its expression is linked to various cancer types and stem cell biology. By utilizing these knockout cell lines, researchers can investigate the functional implications of MSI2 loss on cellular differentiation, proliferation, and tumorigenicity.
The key functionality of MSI2 Gene Knockout Cell Lines lies in their ability to recapitulate the biological consequences of MSI2 gene ablation. This facilitates the examination of gene interaction networks and the pathway alterations that occur in the absence of MSI2. The knockout model serves as a critical tool in elucidating MSI2’s role in oncogenesis, enabling researchers to understand its impact on cancer cell behavior and potentially identify new therapeutic targets.
The scientific importance of these cell lines extends to both fundamental research and clinical applications. In the research setting, they provide an invaluable resource for studying messenger RNA regulation in a controlled environment, especially in contexts related to leukemia and solid tumors. Clinically, understanding the mechanisms by which MSI2 contributes to cancer progression can lead to novel therapeutic strategies, enhancing patient treatment plans and outcomes.
What sets MSI2 Gene Knockout Cell Lines apart from traditional cell culture models is their precision and specificity, reducing the risk of off-target effects commonly associated with older knockout methods. Additionally, the adaptability of these cell lines for various experimental conditions, including drug response assays and gene expression studies, enhances their versatility, making them an essential asset in any researcher's toolkit.
For researchers and clinicians dedicated to advancing cancer biology and therapeutic innovation, the MSI2 Gene Knockout Cell Lines present a unique opportunity to explore cellular mechanisms with accuracy. Backed by our company’s extensive expertise in gene editing technology and commitment to quality, these cell lines promise to accelerate your research endeavors and facilitate breakthroughs in understanding the intricate world of gene regulation.
Please note that all services are for research use only. Not intended for any clinical use.
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