Gene: MSI1
Official Full Name: musashi RNA binding protein 1provided by HGNC
Gene Summary: This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36558 | MSI1 Knockout cell line (HCT 116) | Human | MSI1 | 1:2~1:4 | Negative | Online Inquiry |
KO36559 | MSI1 Knockout cell line (HEK293) | Human | MSI1 | 1:3~1:6 | Negative | Online Inquiry |
MSI1 Gene Knockout Cell Lines are specialized cellular models created through targeted gene editing techniques, specifically CRISPR/Cas9, to effectively disrupt the MSI1 gene's expression. This gene plays a critical role in regulating mRNA stability and translation during cellular processes, particularly in stem cell biology and neural development. By knocking out MSI1, these cell lines allow researchers to elucidate the gene’s mechanisms in both normal physiological and pathological contexts.
The core function of MSI1 knockout cell lines lies in their ability to provide insights into the biological roles of MSI1 in cellular proliferation, differentiation, and response to external stimuli. Researchers can observe changes in signaling pathways, gene expression profiles, and cellular behaviors, which facilitate a deeper understanding of the gene's contribution to phenomena such as cancer progression and neurogenesis. These insights are particularly relevant in both basic research and therapeutic research, where MSI1's implications in various diseases are being investigated.
The scientific importance of these cell lines is evident in their application for drug testing, gene function studies, and developmental biology research. Their use in preclinical studies allows for the identification of potential therapeutic targets, making them invaluable tools in academia and pharmaceutical industries alike. Compared to other available models, the MSI1 Gene Knockout Cell Lines are specifically designed to ensure high efficiency in gene disruption with maintained cell integrity, providing reliable data and reproducibility that are crucial for robust experimental outcomes.
Importantly, these cell lines not only facilitate novel discoveries but also advance translational research, helping bridge the gap between experimental data and clinical application. Researchers and clinicians seeking to explore the intricacies of gene function, disease mechanisms, or drug responses will find these models particularly advantageous.
Our company prides itself on having a strong foundation in providing high-quality biological products tailored to meet the needs of researchers and clinicians. With a commitment to innovation and excellence, we ensure that our MSI1 Gene Knockout Cell Lines are of the highest standard, empowering users to drive forward their scientific inquiries and discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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