Gene: MS4A4E
Official Full Name: membrane spanning 4-domains A4Eprovided by HGNC
Gene Summary: Most MS4A genes, including MS4A4E, encode proteins with at least 4 potential transmembrane domains and N- and C-terminal cytoplasmic domains encoded by distinct exons.[supplied by OMIM, Apr 2004]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16020 | MS4A4E Knockout cell line (HEK293) | Human | MS4A4E | 1:3~1:6 | Negative | Online Inquiry |
MS4A4E Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the expression of the MS4A4E gene, a member of the membrane spanning 4-domains (MS4A) family, which plays a significant role in immune responses and cellular signaling. These knockout cell lines enable researchers to investigate the biological functions of the MS4A4E gene, as well as its implications in various diseases, including autoimmune disorders and cancers.
The key function of the MS4A4E gene is its involvement in the regulation of T-cell activation and proliferation. By employing CRISPR/Cas9 gene editing technology, our MS4A4E knockout cell lines allow for precise gene disruption, which aids in elucidating the signaling pathways and molecular mechanisms that govern immune cell responses. Researchers can utilize these cell lines in assays to assess changes in immune function, cellular interactions, and signaling cascade alterations resulting from the absence of MS4A4E.
The scientific importance of MS4A4E knockout cell lines lies in their potential applications in both basic and translational research settings. They serve as critical tools for understanding T-cell biology, and their role could lead to novel therapeutic targets. In clinical settings, these cell lines could facilitate the development of personalized medicine approaches for conditions linked to dysregulated immune responses.
Compared to alternative models, our MS4A4E knockout cell lines offer high specificity and reliability due to their precise gene editing. These cell lines represent an efficient means of studying the specific role of the MS4A4E gene without the confounding variables present in whole organism models. Researchers can save time and resources while obtaining high-quality data.
In summary, MS4A4E Gene Knockout Cell Lines are invaluable tools for scientists aiming to advance their understanding of immune functions and disease pathways. With our company’s extensive expertise in gene editing technologies and cell line development, we deliver superior products that empower researchers and clinicians in their quest for innovative solutions in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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