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MRTFB Knockout Cell Lines

Gene: MRTFB

Official Full Name: myocardin related transcription factor Bprovided by HGNC

Gene Summary: Enables transcription coactivator activity. Involved in positive regulation of miRNA transcription; positive regulation of striated muscle tissue development; and positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be active in several cellular components, including glutamatergic synapse; postsynapse; and presynapse. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16021 MRTFB Knockout cell line (HeLa) Human MRTFB 1:3~1:6 Negative Online Inquiry
KO16022 MRTFB Knockout cell line (HCT 116) Human MRTFB 1:2~1:4 Negative Online Inquiry
KO16023 MRTFB Knockout cell line (HEK293) Human MRTFB 1:3~1:6 Negative Online Inquiry
KO16024 MRTFB Knockout cell line (A549) Human MRTFB 1:3~1:4 Negative Online Inquiry

Background

MRTFB Gene Knockout Cell Lines are genetically modified cells specifically engineered to lack the MRTFB gene, a critical regulator of cellular processes such as cytoskeletal organization and mechanotransduction. These cell lines serve as powerful tools for researchers seeking to elucidate the functional roles of MRTFB in various biological contexts, including cell signaling, migration, and differentiation.

The key function of MRTFB Gene Knockout Cell Lines revolves around their ability to translate the absence of MRTFB into observable phenotypic changes. By utilizing CRISPR-Cas9 technology, these cell lines facilitate precise gene editing, enabling the analysis of MRTFB's role in both normal physiology and disease mechanisms. Researchers can conduct downstream assays to explore the implications of MRTFB deficiency in processes like tumorigenesis, fibrosis, and vascular development.

The scientific importance of these cell lines extends into various applications, including cancer research, regenerative medicine, and stem cell biology. Their use in experimental protocols can provide robust insights into gene function and regulation, making them invaluable in the quest for novel therapeutic targets. Furthermore, MRTFB Gene Knockout Cell Lines allow for high-throughput screening of compounds that may selectively modulate MRTFB-related pathways.

What sets MRTFB Gene Knockout Cell Lines apart from conventional cell models is their specificity and reliability. Unlike other gene-editing approaches that may introduce off-target effects, these knockout cell lines eliminate the MRTFB gene entirely, ensuring clear, unambiguous results. Researchers benefit from the reproducibility of experiments and the consistent performance of these specialized cell lines, which enhance the reliability of research outcomes.

For researchers, clinicians, and biotech professionals, the availability of MRTFB Gene Knockout Cell Lines represents a significant advancement in elucidating the complexities of gene function and its pathological implications. Our company prides itself on its commitment to scientific excellence, providing researchers with high-quality biological products that empower groundbreaking studies and innovative discoveries in life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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