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MRNIP Knockout Cell Lines

Gene: MRNIP

Official Full Name: MRN complex interacting proteinprovided by HGNC

Gene Summary: Enables chromatin binding activity. Involved in several processes, including mitotic G2 DNA damage checkpoint signaling; regulation of double-strand break repair; and response to ionizing radiation. Located in Mre11 complex and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22939 MRNIP Knockout cell line (HeLa) Human MRNIP 1:3~1:6 Negative Online Inquiry
KO22940 MRNIP Knockout cell line (HCT 116) Human MRNIP 1:2~1:4 Negative Online Inquiry
KO22941 MRNIP Knockout cell line (HEK293) Human MRNIP 1:3~1:6 Negative Online Inquiry
KO22942 MRNIP Knockout cell line (A549) Human MRNIP 1:3~1:4 Negative Online Inquiry

Background

MRNIP Gene Knockout Cell Lines are genetically engineered cellular models designed to enable comprehensive research into the roles and functions of the MRNIP gene. These cell lines are produced through advanced CRISPR-Cas9 technology, which enables precise gene editing to create specific knockout models. By disabling the MRNIP gene, researchers can investigate the cellular pathways and biological processes influenced by its absence, paving the way for insights into various physiological and pathological conditions, including cancer, neurodegenerative disorders, and DNA repair mechanisms.

The primary function of the MRNIP gene is believed to be involved in the regulation of DNA damage responses and the stability of genomic integrity. The intrinsic mechanisms activated in response to MRNIP disruption are of significant interest, as they can elucidate how cells maintain genome fidelity and respond to environmental stressors. This functional understanding presents vast opportunities in both basic and applied biological research, including pharmacological applications and therapeutic development.

What sets MRNIP Gene Knockout Cell Lines apart from alternative models is their specificity and reliability. The targeted nature of CRISPR-Cas9 ensures minimal off-target effects, providing researchers with precise tools for studying gene function. Additionally, the availability of a stable cell line allows for reproducibility in experiments, which is critical for obtaining consistent data across research projects.

These cell lines are invaluable for pharmaceutical and biotechnology companies, academic institutions, and laboratories focused on genetic research and drug development. By utilizing MRNIP Gene Knockout Cell Lines, researchers can gain a deeper understanding of gene function and its implications, significantly enhancing the potential for developing targeted treatments.

With extensive expertise in genetic engineering and molecular biology, our company is committed to delivering high-quality, scientifically robust biological products. We provide researchers with reliable tools that enhance the depth and breadth of their scientific investigations, ultimately driving progress in biomedical research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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