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MRFAP1 Knockout Cell Lines

Gene: MRFAP1

Official Full Name: Morf4 family associated protein 1provided by HGNC

Gene Summary: This gene encodes an intracellular protein that interacts with members of the MORF4/MRG (mortality factor on chromosome 4/MORF4 related gene) family and the tumor suppressor Rb (retinoblastoma protein.) The protein may play a role in senescence, cell growth and immortalization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04998 MRFAP1 Knockout cell line (HeLa) Human MRFAP1 1:3~1:6 Negative Online Inquiry
KO04999 MRFAP1 Knockout cell line (HCT 116) Human MRFAP1 1:2~1:4 Negative Online Inquiry
KO05000 MRFAP1 Knockout cell line (HEK293) Human MRFAP1 1:3~1:6 Negative Online Inquiry
KO05001 MRFAP1 Knockout cell line (A549) Human MRFAP1 1:3~1:4 Negative Online Inquiry

Background

MRFAP1 Gene Knockout Cell Lines represent a cutting-edge biotechnological advancement designed for the specific ablation of the MRFAP1 gene, a crucial player in various cellular processes and signaling pathways. Utilizing CRISPR-Cas9 gene-editing technology, these cell lines allow researchers to create precise, targeted mutations that fully disrupt the MRFAP1 gene's function, effectively eliminating its protein expression. This methodology enhances the ability to study the gene's role in cellular physiology, pathology, and therapeutic responsiveness.

The primary function of MRFAP1 involves its participation in the regulation of transcription and cellular signaling pathways. By utilizing these knockout cell lines, investigators can explore the downstream effects of MRFAP1 ablation, providing insights into its involvement in disease mechanisms, including cancer and metabolic disorders. This tool is essential for functional genomics, allowing for the exploration of gene function in specific cellular contexts and aiding in the identification of potential therapeutic targets.

In terms of scientific importance, MRFAP1 Gene Knockout Cell Lines are valuable for both in vitro and potential ex vivo applications. Their utility ranges from drug discovery to genetic studies, enabling researchers to swiftly assess the phenotypic consequences of gene loss under controlled experimental conditions. Compared to alternative methods such as siRNA-based gene knockdown or traditional knockout techniques, these cell lines offer a more robust and stable solution with higher specificity and efficiency in disrupting gene function.

For researchers and clinicians, the availability of MRFAP1 Gene Knockout Cell Lines translates into significant time savings and enhanced project outcomes. Their precision and reliability make them an indispensable asset for laboratories focused on advancing the understanding of MRFAP1-related pathways and developing novel therapeutic strategies.

With extensive experience in producing high-quality gene-editing products, our company is dedicated to empowering research efforts with state-of-the-art tools such as MRFAP1 Gene Knockout Cell Lines, which are backed by rigorous scientific validation and technical support. We strive to contribute meaningfully to the scientific community by facilitating innovative research and discovery processes.

Please note that all services are for research use only. Not intended for any clinical use.

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