Gene: MRAP2
Official Full Name: melanocortin 2 receptor accessory protein 2provided by HGNC
Gene Summary: This gene encodes a protein that modulates melanocortin receptor signaling. The encoded protein has been shown to interact with all known melanocortin receptors and may regulate both receptor trafficking and activation in response to ligands. Mice lacking a functional copy of this gene exhibit severe obesity and a mutation in this gene may be associated with severe obesity in human patients. [provided by RefSeq, Oct 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30930 | MRAP2 Knockout cell line (HeLa) | Human | MRAP2 | 1:3~1:6 | Negative | Online Inquiry |
KO30931 | MRAP2 Knockout cell line (HCT 116) | Human | MRAP2 | 1:2~1:4 | Negative | Online Inquiry |
KO30932 | MRAP2 Knockout cell line (HEK293) | Human | MRAP2 | 1:3~1:6 | Negative | Online Inquiry |
KO30933 | MRAP2 Knockout cell line (A549) | Human | MRAP2 | 1:3~1:4 | Negative | Online Inquiry |
MRAP2 Gene Knockout Cell Lines are advanced genetically modified cell lines designed for the comprehensive study of the melanocortin receptor accessory protein 2 (MRAP2). This product enables researchers to explore the functional implications of MRAP2 deficiency, offering crucial insights into its role in the regulation of energy homeostasis and appetite modulation. By employing CRISPR/Cas9 technology for the specific knockout of the MRAP2 gene, these cell lines allow for targeted investigations into the signaling pathways mediated by melanocortin receptors, which have significant implications in metabolic disorders.
The MRAP2 gene encodes a protein that is critical for the proper functioning of melanocortin receptors, which are involved in various physiological processes including energy balance, stress responsiveness, and circadian rhythms. By utilizing these knockout cell lines, researchers can elucidate the molecular mechanisms underlying these functions, paving the way for novel therapeutic targets in obesity and related metabolic diseases.
In comparison to conventional gene silencing techniques, MRAP2 Gene Knockout Cell Lines offer a more permanent and precise approach to studying gene function. This specificity not only enhances reproducibility but also minimizes off-target effects commonly associated with alternative methods, such as siRNA. Moreover, these cell lines come with the assurance of rigorous validation and characterization, ensuring that researchers can rely on consistent performance during their experiments.
For researchers and clinicians engaged in metabolic research, these MRAP2 Gene Knockout Cell Lines represent an invaluable tool for exploring the complexities of energy metabolism. They provide essential data that can contribute to the development of innovative interventions for obesity and other metabolic syndromes.
Our company specializes in producing high-quality, genetically modified cell lines developed through cutting-edge techniques in genetic engineering, ensuring that our customers have access to superior research tools tailored for their investigative needs.
Please note that all services are for research use only. Not intended for any clinical use.
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