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MPDZ Knockout Cell Lines

Gene: MPDZ

Official Full Name: multiple PDZ domain crumbs cell polarity complex componentprovided by HGNC

Gene Summary: The protein encoded by this gene has multiple PDZ domains, which are hallmarks of protein-protein interactions. The encoded protein is known to interact with the HTR2C receptor and may cause it to clump at the cell surface. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33874 MPDZ Knockout cell line (HeLa) Human MPDZ 1:3~1:6 Negative Online Inquiry
KO33875 MPDZ Knockout cell line (HEK293) Human MPDZ 1:3~1:6 Negative Online Inquiry
KO33876 MPDZ Knockout cell line (A549) Human MPDZ 1:3~1:4 Negative Online Inquiry

Background

MPDZ Gene Knockout Cell Lines are an innovative tool designed to study the biological functions of the MPDZ gene through the targeted inactivation of its expression in mammalian cell lines. This product leverages CRISPR-Cas9 technology, a cutting-edge genome-editing approach that introduces precise mutations into the MPDZ gene, thereby facilitating the investigation of its role in various cellular processes including cell adhesion, signaling pathways, and excitability.

The primary functions of MPDZ Gene Knockout Cell Lines arise from their ability to mimic the physiological conditions of specific diseases or cellular behaviors in vitro. By eliminating the MPDZ gene, researchers can observe the resultant phenotypic changes which provide critical insights into the gene's contribution to pathological states or various physiological mechanisms. This advanced understanding opens new avenues for developing therapeutic strategies targeting the MPDZ gene and related pathways.

The scientific importance of these knockout cell lines extends to both fundamental research and clinical applications. In basic research, they are vital for unraveling the complexities of gene interactions and signaling networks. Clinically, they hold potential for advancing our knowledge in fields such as cancer biology, neuroscience, and cardiovascular diseases, where MPDZ is implicated.

What sets MPDZ Gene Knockout Cell Lines apart from traditional knockouts or other gene-editing approaches is their precision and reliability. Each line is extensively validated for efficient gene disruption and corresponding loss of function, ensuring reproducible results for downstream applications. Additionally, these cell lines are readily adaptable to various experimental conditions, supporting a wide range of assays from drug screening to mechanistic studies.

For researchers and clinicians, the utility of the MPDZ Gene Knockout Cell Lines cannot be overstated. They provide a powerful platform for exploring gene function, identifying therapeutic targets, and validating drug effects, ultimately fostering innovation in biomedical research. Our company specializes in delivering high-quality biological products backed by robust scientific evidence and expertise in gene manipulation technologies, ensuring that our offerings meet the evolving needs of the research community.

Please note that all services are for research use only. Not intended for any clinical use.

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