Gene: MORC2
Official Full Name: MORC family CW-type zinc finger 2provided by HGNC
Gene Summary: This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in repressing transcription. The protein has been found to regulate the activity of ATP citrate lyase via specific interaction with this enzyme in the cytosol of lipogenic breast cancer cells. The protein also plays a role in lipogenesis and adipocyte differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
GP00308 | MORC2 gRNA3-gRNA4 KO plasmid | MORC2 | $850 | |||
GP00317 | MORC2 gRNA1-gRNA2 KO plasmid | MORC2 | $850 | |||
KO00693 | MORC2 Knockout cell line (HeLa) | Human | MORC2 | 1:3~1:6 | Negative | Online Inquiry |
KO03692 | MORC2 Knockout cell line (HCT 116) | Human | MORC2 | 1:2~1:4 | Negative | Online Inquiry |
KO03693 | MORC2 Knockout cell line (HEK293) | Human | MORC2 | 1:3~1:6 | Negative | Online Inquiry |
KO03694 | MORC2 Knockout cell line (A549) | Human | MORC2 | 1:3~1:4 | Negative | Online Inquiry |
MORC2 Gene Knockout Cell Lines are specialized genetic models designed to facilitate the study of the MORC2 gene, which plays a pivotal role in various cellular processes, including chromatin remodeling, transcription regulation, and DNA damage response. These cell lines have been specifically engineered to eliminate the expression of the MORC2 gene, allowing researchers to meticulously analyze the resultant phenotypic and molecular changes. Through techniques such as CRISPR-Cas9 genome editing, the MORC2 knockout model provides a robust platform for probing the biological functions of this gene and its implications in diseases where its dysregulation is implicated.
The primary mechanism of these cell lines revolves around the complete abrogation of MORC2 activity, which enables the study of epigenetic alterations and cellular pathways that may otherwise remain obscured in wild-type cells. By observing how the knockout cells respond to environmental stimuli, stressors, or therapeutic agents, researchers can gain valuable insights into the gene’s contributions to cellular homeostasis and disease progression, particularly in cancer and other proliferative disorders.
The scientific importance of MORC2 Gene Knockout Cell Lines extends to fundamental research and potential clinical applications. They serve as invaluable tools for drug discovery, enabling scientists to identify novel therapeutic strategies and biomarkers for precision medicine. Moreover, these cell lines can assist in unraveling the molecular mechanisms underlying genetic diseases, offering pathways for the development of gene-targeted therapies.
One of the unique selling points of our MORC2 Gene Knockout Cell Lines is their ease of use and reliability. Unlike alternatives that may involve laborious procedures or less efficient knockout techniques, our models come ready for experimentation, minimizing the time and resources required to achieve desired results. Additionally, they are compatible with a variety of assays, including gene expression analyses, cellular assays, and in vivo studies, thereby enhancing their versatility in diverse research settings.
Given the increasing focus on the role of specific genes in health and disease, the MORC2 Gene Knockout Cell Lines stand out as an essential asset for researchers and clinicians striving to deepen their understanding of genetic interactions and therapeutic targets. Our company prides itself on delivering high-quality biological products backed by rigorous scientific research and expertise, ensuring that users can rely on our solutions for their most pressing research challenges.
Please note that all services are for research use only. Not intended for any clinical use.
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