Gene: MOAP1
Official Full Name: modulator of apoptosis 1provided by HGNC
Gene Summary: The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16126 | MOAP1 Knockout cell line (HeLa) | Human | MOAP1 | 1:3~1:6 | Negative | Online Inquiry |
KO16127 | MOAP1 Knockout cell line (HCT 116) | Human | MOAP1 | 1:2~1:4 | Negative | Online Inquiry |
KO16128 | MOAP1 Knockout cell line (HEK293) | Human | MOAP1 | 1:3~1:6 | Negative | Online Inquiry |
KO16129 | MOAP1 Knockout cell line (A549) | Human | MOAP1 | 1:3~1:4 | Negative | Online Inquiry |
MOAP1 Gene Knockout Cell Lines are genetically engineered cellular models designed to study the implications of the MOAP1 gene in various biological processes. MOAP1 (Motif 1 of Apoptosis) plays a crucial role in the regulation of apoptosis and cell survival, making these knockout cell lines invaluable for researchers exploring cancer biology, neurodegenerative diseases, and therapeutic interventions targeting apoptotic pathways. By disabling the MOAP1 gene, these cell lines facilitate the examination of the downstream effects on protein interactions and signaling cascades, providing insights into cellular responses to stressors and the potential for enhanced cell survival under specific conditions.
The key function of MOAP1 involves its interaction with pro-apoptotic and anti-apoptotic members of the Bcl-2 family, thereby influencing mitochondrial integrity and apoptotic signaling. By using MOAP1 knockout cell lines, researchers can gain a deeper understanding of how the loss of this gene alters apoptosis regulation, cell proliferation, and resistance to chemotherapeutic agents. This can be pivotal in identifying new therapeutic targets for cancer treatment, wherein apoptosis evasion is a common mechanism of resistance.
The scientific importance of MOAP1 Gene Knockout Cell Lines extends into various applications in research and clinical settings, including drug discovery, cancer research, and the investigation of genetic influences on disease mechanisms. Unlike alternative cellular models, these knockout lines provide an equilibrium of ease and experimental control, allowing for reproducibility and reliability in results.
This product offers specific advantages by enabling researchers to closely examine the role of the MOAP1 gene without confounding factors. Additionally, our cell lines are characterized by their high purity and consistent performance across experiments. This positions them as a leading choice for researchers seeking clarity in their studies of apoptotic pathways.
By utilizing our MOAP1 Gene Knockout Cell Lines, researchers and clinicians can harness the full potential of this revolutionary tool to advance their understanding of apoptosis and its implications in various diseases. Our company specializes in creating precision genetic tools that empower scientific exploration, reflecting our commitment to facilitating groundbreaking research and therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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