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MMEL1 Knockout Cell Lines

Gene: MMEL1

Official Full Name: membrane metalloendopeptidase like 1provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23365 MMEL1 Knockout cell line (HCT 116) Human MMEL1 1:2~1:4 Negative Online Inquiry

Background

MMEL1 Gene Knockout Cell Lines are meticulously engineered cellular models designed to study the function of the melanocyte master regulator gene, MMEL1 (Melanocyte Master Enhancer 1). Utilizing advanced CRISPR-Cas9 technology, these cell lines exhibit precise gene knockout, facilitating an in-depth exploration of MMEL1's role in cellular processes such as pigmentation, differentiation, and signaling pathways.

The key function of MMEL1 Gene Knockout Cell Lines lies in their ability to accurately model the effects of MMEL1 in various physiological contexts. By eliminating the expression of MMEL1, researchers can elucidate its biological roles and determine how its absence influences cellular behavior, gene expression profiles, and response to environmental stimuli. This knockout model aids in understanding conditions such as pigmentation disorders, melanoma progression, and cellular stress responses.

The scientific importance of these cell lines is particularly evident in both research and clinical settings. In academic research, they serve as valuable tools for studying gene function, epigenetics, and potential therapeutic targets, paving the way for novel treatments. Clinically, understanding MMEL1's involvement in melanocyte biology can lead to innovative strategies for managing skin diseases and melanoma, ultimately improving patient outcomes.

Compared to traditional methods of gene manipulation, MMEL1 Gene Knockout Cell Lines offer several distinct advantages. They are ready-to-use, save valuable research time, and ensure reproducibility across experiments, eliminating the need for de novo gene editing. Furthermore, their robust characterization guarantees consistent performance, allowing researchers to focus on their experimental goals rather than troubleshooting gene editing processes.

For researchers, clinicians, and pharmaceutical companies alike, the MMEL1 Gene Knockout Cell Lines present an invaluable resource for advancing our understanding of melanocyte biology and developing targeted therapies. Our company is dedicated to providing high-quality biological products, supported by a team of experts in gene editing and cell biology, ensuring our offerings meet the rigorous demands of modern research.

Please note that all services are for research use only. Not intended for any clinical use.

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