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MLLT10 Knockout Cell Lines

Gene: MLLT10

Official Full Name: MLLT10 histone lysine methyltransferase DOT1L cofactorprovided by HGNC

Gene Summary: This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34337 MLLT10 Knockout cell line (HeLa) Human MLLT10 1:3~1:6 Negative Online Inquiry
KO34338 MLLT10 Knockout cell line (HCT 116) Human MLLT10 1:2~1:4 Negative Online Inquiry
KO34339 MLLT10 Knockout cell line (HEK293) Human MLLT10 1:3~1:6 Negative Online Inquiry
KO34340 MLLT10 Knockout cell line (A549) Human MLLT10 1:3~1:4 Negative Online Inquiry

Background

MLLT10 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to facilitate the study of MLLT10 function and its implications in various biological processes and diseases. This product involves the precise deletion of the MLLT10 gene, which encodes a protein implicated in chromatin remodeling and transcriptional regulation. By utilizing techniques such as CRISPR-Cas9, these knockout cell lines enable researchers to investigate the phenotypic consequences of MLLT10 loss, including its role in oncogenesis, cellular differentiation, and response to therapies.

The primary function of MLLT10 lies in its involvement with chromatin structure and gene expression regulation, making it a critical target in understanding its aberrant function in cancers, particularly acute leukemia. Researchers can employ these cell lines to study signaling pathways, cellular metabolism, and gene expression profiles altered by MLLT10 deficiency. The mechanisms through which MLLT10 responds to various external stimuli can be elucidated using this tool, thereby paving the way for novel therapeutic strategies.

The significance of MLLT10 Gene Knockout Cell Lines extends beyond basic research; they serve as valuable models in drug discovery and development, allowing for the identification of potential therapeutic targets and biomarkers in cancer treatment. By providing a clearer understanding of MLLT10-related pathways, these cell lines contribute meaningfully to the clinical landscape.

Compared to general knockout cell lines, MLLT10-specific lines offer a unique advantage due to their targeted approach, reducing background variables and enhancing the specificity of experimental outcomes. This specificity allows for highly controlled studies, leading to more reliable results and reproducibility, key factors in today’s rigorous research environment.

Researchers and clinicians utilizing MLLT10 Gene Knockout Cell Lines benefit from the precision and depth of insight these models offer, enhancing experimental reproducibility and driving innovation in related fields. Our company prides itself on providing high-quality, well-characterized biological products that empower researchers in their scientific endeavors. With a commitment to advancing biological research, we support the scientific community by delivering state-of-the-art tools tailored to meet the contemporary challenges of biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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