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MINDY4 Knockout Cell Lines

Gene: MINDY4

Official Full Name: MINDY lysine 48 deubiquitinase 4provided by HGNC

Gene Summary: Predicted to enable K48-linked deubiquitinase activity. Predicted to be involved in protein K48-linked deubiquitination and proteolysis. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25133 MINDY4 Knockout cell line (HeLa) Human MINDY4 1:3~1:6 Negative Online Inquiry
KO25134 MINDY4 Knockout cell line (HCT 116) Human MINDY4 1:2~1:4 Negative Online Inquiry
KO25135 MINDY4 Knockout cell line (HEK293) Human MINDY4 1:3~1:6 Negative Online Inquiry
KO25136 MINDY4 Knockout cell line (A549) Human MINDY4 1:3~1:4 Negative Online Inquiry

Background

MINDY4 Gene Knockout Cell Lines are a cutting-edge tool designed for targeted genetic manipulation, specifically developed to facilitate the study of gene function in mammalian cells. These cell lines have been engineered to produce a functional knockout of the MINDY4 gene, allowing researchers to explore the physiological and pathological roles this gene plays in various biological processes. Utilizing advanced CRISPR/Cas9 technology, MINDY4 Gene Knockout Cell Lines enable precise alterations to the genome, ensuring reproducibility and specificity in experimental outcomes.

The key mechanism behind MINDY4 Gene Knockout Cell Lines involves the introduction of guide RNA sequences that direct the Cas9 nuclease to targeted location within the gene of interest. Once the gene is cut, the cell's repair mechanisms are activated, leading to insertion or deletion mutations that effectively silence the gene's expression. This targeted approach provides researchers with powerful insights into gene function, regulation, and the biochemical pathways involved in disease.

The scientific significance of these cell lines cannot be overstated, as they open avenues for groundbreaking research in gene therapy, cancer biology, and regenerative medicine. Additionally, the MINDY4 knockout cell lines serve as essential models for drug development and screening, allowing for the identification of novel therapeutic targets and the assessment of drug efficacy in a controlled environment.

Compared to traditional knockout methods, such as homologous recombination, MINDY4 Gene Knockout Cell Lines offer superior advantages in terms of time efficiency, accuracy, and ease of use. The high-throughput capabilities of the CRISPR approach mean researchers can develop knockout models rapidly, expediting the research timeline significantly. Furthermore, the cell lines come with extensive validation data, ensuring reliable usage and consistent results.

For researchers, clinicians, and biotechnologists, the value of MINDY4 Gene Knockout Cell Lines lies in their potential to accelerate discovery in genetic and biomedical research. With the ability to dissect complex cellular mechanisms, these cell lines are indispensable for anyone focused on the frontiers of molecular biology and genetic engineering.

The commitment of our company to excellence in the field of biological products is evident in our continuous investment in state-of-the-art technologies and rigorous quality control measures. This ensures that our offerings, including the MINDY4 Gene Knockout Cell Lines, meet the highest standards of performance and reliability in scientific research.

Please note that all services are for research use only. Not intended for any clinical use.

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