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MINDY3 Knockout Cell Lines

Gene: MINDY3

Official Full Name: MINDY lysine 48 deubiquitinase 3provided by HGNC

Gene Summary: The protein encoded by this gene contains a caspase-associated recruitment domain and may function in apoptosis. It has been identified as a tumor suppressor in lung and gastric cancers, and a polymorphism in the gene may be associated with gastric cancer risk. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26303 MINDY3 Knockout cell line (HeLa) Human MINDY3 1:3~1:6 Negative Online Inquiry
KO26304 MINDY3 Knockout cell line (HCT 116) Human MINDY3 1:2~1:4 Negative Online Inquiry
KO26305 MINDY3 Knockout cell line (HEK293) Human MINDY3 1:3~1:6 Negative Online Inquiry
KO26306 MINDY3 Knockout cell line (A549) Human MINDY3 1:3~1:4 Negative Online Inquiry

Background

MINDY3 Gene Knockout Cell Lines are specialized biological tools derived from genetically modified cell lines, specifically designed to provide researchers with a powerful means to study the functions of the MINDY3 gene. This gene has been implicated in various biological processes, including protein degradation and cellular stress responses, making the knock-out models invaluable for elucidating its role in both normal physiological conditions and disease states.

The key function of MINDY3 Gene Knockout Cell Lines involves the complete disruption of the MINDY3 gene, enabling researchers to observe the resulting phenotypic changes and underlying molecular mechanisms. This facilitates an in-depth analysis of gene function, signaling pathways, and potential interactions with other cellular components. By utilizing CRISPR-Cas9 technology or other gene-editing techniques, these cell lines provide precise and reproducible models that enhance the reliability of experimental outcomes.

Scientifically, MINDY3 Gene Knockout Cell Lines are critical in research settings focused on cellular metabolism, neurodegenerative diseases, and cancer biology. They serve as a platform for drug discovery and therapeutic development, allowing for the identification of potential targets and the evaluation of pharmacological interventions. Furthermore, their applications extend to basic research in cell biology, genetics, and molecular pathways, making them a versatile asset in any research laboratory.

When compared to traditional gene knockouts or knockdowns, MINDY3 Gene Knockout Cell Lines offer several advantages. They provide a complete loss-of-function model that is essential for understanding gene roles more effectively than partial knockdowns can. Moreover, the stability and consistency of these cell lines enhance reproducibility across experiments, significantly reducing variability and increasing the robustness of findings.

For researchers and clinicians seeking to uncover the complexities of gene function, MINDY3 Gene Knockout Cell Lines represent an essential resource, enabling groundbreaking discoveries and advancements in the understanding of health and disease mechanisms. Our company possesses extensive expertise in producing high-quality biological products, ensuring that every cell line we offer meets stringent scientific standards while facilitating your research goals.

Please note that all services are for research use only. Not intended for any clinical use.

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