Gene: MINDY2
Official Full Name: MINDY lysine 48 deubiquitinase 2provided by HGNC
Gene Summary: Enables peptidase activity and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in chromatin remodeling and proteolysis. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21579 | MINDY2 Knockout cell line (HeLa) | Human | MINDY2 | 1:3~1:6 | Negative | Online Inquiry |
KO21580 | MINDY2 Knockout cell line (HCT 116) | Human | MINDY2 | 1:2~1:4 | Negative | Online Inquiry |
KO21581 | MINDY2 Knockout cell line (HEK293) | Human | MINDY2 | 1:3~1:6 | Negative | Online Inquiry |
KO21582 | MINDY2 Knockout cell line (A549) | Human | MINDY2 | 1:3~1:4 | Negative | Online Inquiry |
MINDY2 Gene Knockout Cell Lines are specifically engineered cellular models that have undergone targeted genome editing to disrupt the MINDY2 gene, a crucial component involved in cellular processes such as protein recycling and autophagy. These knockout cell lines serve as pivotal tools in elucidating the functional role of the MINDY2 protein in various biological contexts. By creating a controlled cellular environment devoid of MINDY2, researchers can assess the downstream effects and pathways modulated by this gene, thereby providing insights into its contributions to diseases, including cancer and neurodegenerative disorders.
The key mechanism of MINDY2 gene knockout revolves around CRISPR-Cas9 technology, a revolutionary gene-editing methodology. This precise approach not only facilitates the efficient creation of knockout models but also minimizes off-target effects, ensuring that the modifications are specific and reliable. The knockout of MINDY2 allows scientists to dissect complex cellular mechanisms and contributes to a better understanding of disease etiology.
The scientific importance of MINDY2 Gene Knockout Cell Lines in research is profound. They are invaluable for drug discovery initiatives, toxicological studies, and functional genomics research due to the ability to provide a clean genetic background devoid of the target gene's activity. Additionally, these cell lines can be employed in therapeutic contexts, making them essential for the validation of gene-targeted therapies and biomarkers.
Compared to alternative models such as transient transfection or whole-animal studies, MINDY2 Gene Knockout Cell Lines offer several advantages. They provide a stable and reproducible cellular platform, enabling high-throughput screening and facilitating easier comparisons across experiments. This leads to more reliable data and robust conclusions, which are crucial for advancing research.
For researchers and clinicians alike, MINDY2 Gene Knockout Cell Lines represent an innovative product that opens doors to exploring novel therapeutic avenues and improving our understanding of cellular mechanisms. As a leader in the realm of biological products, our company is committed to delivering high-quality, reliable, and scientifically rigorous tools that support cutting-edge research initiatives and clinical applications. With a strong background in genomics and cell biology, we pride ourselves on equipping scientists with the resources necessary to drive discovery and innovation in their work.
Please note that all services are for research use only. Not intended for any clinical use.
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