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MIGA2 Knockout Cell Lines

Gene: MIGA2

Official Full Name: mitoguardin 2provided by HGNC

Gene Summary: Enables protein heterodimerization activity and protein homodimerization activity. Involved in mitochondrial fusion. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24543 MIGA2 Knockout cell line (HeLa) Human MIGA2 1:3~1:6 Negative Online Inquiry
KO24544 MIGA2 Knockout cell line (HCT 116) Human MIGA2 1:2~1:4 Negative Online Inquiry
KO24545 MIGA2 Knockout cell line (HEK293) Human MIGA2 1:3~1:6 Negative Online Inquiry
KO24546 MIGA2 Knockout cell line (A549) Human MIGA2 1:3~1:4 Negative Online Inquiry

Background

MIGA2 Gene Knockout Cell Lines are genetically engineered cellular models designed to specifically lack the MIGA2 gene, allowing researchers to study the functional roles of this gene in various biological processes. These cell lines are generated using advanced CRISPR-Cas9 gene-editing technology, which offers precise and efficient gene knockout capabilities. The targeted deletion of the MIGA2 gene facilitates in-depth investigation into its contributions to cellular signaling pathways, gene expression regulation, and overall cellular physiology, making it an essential tool for molecular biology and genetics research.

The key mechanism behind MIGA2 knockout cell lines involves the specific disruption of the gene coding for the MIGA2 protein, which has been implicated in various cellular functions, including cellular adhesion and migration, which are critical to tissue development and response to injury. By utilizing these knockout cell lines, scientists can elucidate the phenotypic changes resulting from the absence of MIGA2, thus advancing our understanding of its role in health and disease, particularly in cancer biology and regenerative medicine.

The scientific importance of MIGA2 knockout cell lines extends to both fundamental research and applied clinical settings. Researchers can employ these models to explore potential therapeutic targets and validate hypotheses concerning gene function in disease processes. Moreover, they serve as valuable tools for drug testing, allowing for the assessment of responses to treatment in a controlled genetic environment.

One of the significant advantages of MIGA2 knockout cell lines is their high specificity and reproducibility compared to conventional methods such as RNA interference, which can have off-target effects. Additionally, the speed and efficiency of CRISPR-Cas9 technology make these cell lines quickly attainable for experimental use. These features contribute to reliable experimental outcomes, crucial for high-stakes research and development.

Target users, including academic researchers, biotechnology companies, and clinical laboratories, will find MIGA2 knockout cell lines invaluable for their ability to accelerate scientific discovery while minimizing experimental variability and potential confounding factors.

Our company specializes in providing high-quality genomic tools and resources for the life sciences community. With a commitment to innovation and excellence, we offer a comprehensive range of products geared towards enhancing research efficiency and outcomes, ensuring that our clientele remains at the forefront of scientific advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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