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MIER1 Knockout Cell Lines

Gene: MIER1

Official Full Name: MIER1 transcriptional regulatorprovided by HGNC

Gene Summary: This gene encodes a protein that was first identified in Xenopus laevis by its role in a mesoderm induction early response (MIER). The encoded protein functions as a transcriptional regulator. Alternatively spliced transcript variants encode multiple isoforms, some of which lack a C-terminal nuclear localization signal. [provided by RefSeq, May 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16169 MIER1 Knockout cell line (HeLa) Human MIER1 1:3~1:6 Negative Online Inquiry
KO16170 MIER1 Knockout cell line (HCT 116) Human MIER1 1:2~1:4 Negative Online Inquiry
KO16171 MIER1 Knockout cell line (HEK293) Human MIER1 1:3~1:6 Negative Online Inquiry
KO16172 MIER1 Knockout cell line (A549) Human MIER1 1:3~1:4 Negative Online Inquiry

Background

MIER1 Gene Knockout Cell Lines are a cutting-edge biotechnological tool designed to facilitate the investigation of the MIER1 gene's role in various biological processes and potential disease states. These cell lines have been engineered using CRISPR-Cas9 technology to disrupt the MIER1 gene, thereby enabling researchers to study the downstream effects of MIER1 loss-of-function in a controlled environment.

The primary function of these knockout cell lines lies in their ability to elucidate gene function and regulatory mechanisms. Upon disruption of the MIER1 gene, researchers can monitor changes in cellular behavior, including alterations in protein expression, signaling pathways, and metabolic processes. Such applications are pivotal in understanding MIER1's involvement in processes such as cell proliferation, differentiation, and apoptosis. This knowledge can significantly impact research in cancer biology, developmental biology, and regenerative medicine.

The scientific importance of MIER1 Gene Knockout Cell Lines extends to both academic research and clinical settings. They serve as powerful models to investigate genetic contributions to disease states, enabling the development of targeted therapies and novel therapeutic strategies. Their application can also enhance drug screening processes, providing a robust platform for testing the efficacy of potential compounds in a genetically defined context.

What sets our MIER1 Gene Knockout Cell Lines apart from alternative models is their precise editing, reproducibility, and validation. Each cell line is curated with rigorous quality control measures, ensuring that the genetic alteration is stable and well-characterized. This reliability fosters confidence in experimental outcomes, minimizing variability that can arise from using less rigorously developed models.

For researchers and clinicians, the value of these cell lines lies in their ability to accelerate discovery and deepen understanding, ultimately driving advancements in therapeutic development. By utilizing MIER1 Gene Knockout Cell Lines, scientists gain a critical resource that enhances the precision of their investigations and informs translational research efforts.

As a leader in the biotechnology field, our company is committed to delivering high-quality products that empower researchers to push the boundaries of scientific understanding. Our expertise, coupled with a commitment to innovation, positions us as a valued partner in advancing biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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