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MEX3B Knockout Cell Lines

Gene: MEX3B

Official Full Name: mex-3 RNA binding family member Bprovided by HGNC

Gene Summary: This gene encodes an RNA-binding phosphoprotein that is part of the MEX3 (muscle excess 3) family of translational regulators. The encoded protein contains N-terminal nuclear export and nuclear localization signals and is exported from the cytoplasm to the nucleus. The protein binds to RNA via two KH domains and also colocalizes with MEX3A, Dcp1A decapping factor and Argonaute proteins within P (processing) bodies. [provided by RefSeq, Oct 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25099 MEX3B Knockout cell line (HeLa) Human MEX3B 1:3~1:6 Negative Online Inquiry
KO25100 MEX3B Knockout cell line (HCT 116) Human MEX3B 1:2~1:4 Negative Online Inquiry
KO25101 MEX3B Knockout cell line (HEK293) Human MEX3B 1:3~1:6 Negative Online Inquiry
KO25102 MEX3B Knockout cell line (A549) Human MEX3B 1:3~1:4 Negative Online Inquiry

Background

MEX3B Gene Knockout Cell Lines are advanced research tools designed to facilitate the in-depth study of the MEX3B gene, which encodes for a member of the MEX3 family of RNA-binding proteins involved in various cellular processes such as RNA metabolism, translation regulation, and signal transduction. By employing CRISPR/Cas9 gene editing technologies, these knockout cell lines provide a unique opportunity to analyze the functional implications of MEX3B loss in cellular contexts and contribute significantly to the understanding of its role in both normal physiology and disease states.

The key functionality of the MEX3B Gene Knockout Cell Lines lies in their ability to alter cellular behavior by selectively silencing the MEX3B gene. This results in the perturbation of related signaling cascades and RNA regulation mechanisms, effectively allowing researchers to probe the gene's role in processes like cell proliferation, differentiation, and apoptosis. By utilizing these cell lines, scientists can assess the phenotypic consequences of gene knockout, offering insights that are critical for elucidating the underlying molecular pathways involved in various cancers and degenerative diseases.

The scientific importance of these cell lines is immense, particularly in research and clinical settings where understanding gene function is crucial. These knockout models are invaluable for drug discovery and development efforts, aiding in the identification of new therapeutic targets. In laboratory settings, they can be utilized to screen for candidate compounds that modulate MEX3B-related pathways, thus contributing to a personalized medicine approach.

What sets MEX3B Gene Knockout Cell Lines apart from alternatives is their high specificity and efficiency, derived from rigorous validation processes. The precision of CRISPR/Cas9 technology ensures that off-target effects are minimized, providing researchers with reliable data. Our product also features robust customer support and detailed user protocols, which facilitate smooth integration into ongoing research workflows.

For researchers and clinicians seeking to uncover the functionalities of the MEX3B gene, our knockout cell lines are indispensable tools that empower innovative approaches to modern biology. Additionally, our company prides itself on its commitment to excellence in genetic engineering, offering a suite of high-quality biological products that are backed by extensive expertise in the field.

Please note that all services are for research use only. Not intended for any clinical use.

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