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METTL6 Knockout Cell Lines

Gene: METTL6

Official Full Name: methyltransferase 6, tRNA N3-cytidineprovided by HGNC

Gene Summary: Enables enzyme binding activity and tRNA (cytidine-3-)-methyltransferase activity. Involved in tRNA methylation. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26548 METTL6 Knockout cell line (HeLa) Human METTL6 1:3~1:6 Negative Online Inquiry
KO26549 METTL6 Knockout cell line (HCT 116) Human METTL6 1:2~1:4 Negative Online Inquiry
KO26550 METTL6 Knockout cell line (HEK293) Human METTL6 1:3~1:6 Negative Online Inquiry
KO26551 METTL6 Knockout cell line (A549) Human METTL6 1:3~1:4 Negative Online Inquiry

Background

METTL6 Gene Knockout Cell Lines are genetically modified cell models specifically designed to facilitate the study of METTL6, a methyltransferase involved in RNA methylation processes. This innovative product allows researchers to create a comprehensive understanding of the functional roles of METTL6 in cellular responses, gene expression regulation, and various biological pathways influenced by RNA modifications. By utilizing CRISPR-Cas9 technology, these cell lines ensure precise and effective knockout of the METTL6 gene, providing a robust platform for investigating gene function in both basic and translational research.

The primary mechanism of action of METTL6 is through the transfer of methyl groups to RNA molecules, impacting their stability, translation, and splicing. Disruption of METTL6 expression can lead to significant alterations in the cellular transcriptome and ultimately influence cell fate. This makes METTL6 Gene Knockout Cell Lines highly valuable for studies focusing on epitranscriptomics, cancer biology, and RNA metabolic processes.

In scientific and clinical settings, these cell lines are particularly important for understanding diseases associated with dysregulated RNA methylation, such as certain cancers and neurological disorders. Their utility extends to drug discovery, where the modulation of METTL6 activity could reveal novel therapeutic targets.

What sets METTL6 Gene Knockout Cell Lines apart from alternative products is the assurance of high specificity and efficiency in gene editing, along with the offered technical support for experimental design. Additionally, the reproducibility and consistency of results obtained from these cell lines promote confidence in data interpretation.

Researchers and clinicians will find significant value in these cell lines, as they provide foundational tools for elucidating the roles of METTL6 in health and disease. Furthermore, our company brings years of expertise in developing high-quality biological products, complemented by a commitment to supporting the scientific community through innovative solutions to advance research capabilities.

Please note that all services are for research use only. Not intended for any clinical use.

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