Gene: METTL2A
Official Full Name: methyltransferase 2A, tRNA N3-cytidineprovided by HGNC
Gene Summary: Enables tRNA (cytidine-3-)-methyltransferase activity. Involved in tRNA methylation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16240 | METTL2A Knockout cell line (HeLa) | Human | METTL2A | 1:3~1:6 | Negative | Online Inquiry |
KO16241 | METTL2A Knockout cell line (HCT 116) | Human | METTL2A | 1:2~1:4 | Negative | Online Inquiry |
KO16242 | METTL2A Knockout cell line (HEK293) | Human | METTL2A | 1:3~1:6 | Negative | Online Inquiry |
KO16243 | METTL2A Knockout cell line (A549) | Human | METTL2A | 1:3~1:4 | Negative | Online Inquiry |
METTL2A Gene Knockout Cell Lines are essential research tools created through advanced genetic engineering techniques. These cell lines feature a targeted knockout of the METTL2A gene, which encodes a methyltransferase involved in regulating RNA methylation processes. By silencing METTL2A, researchers can study the gene's role in various cellular functions, including RNA metabolism, translation efficiency, and cellular stress response mechanisms.
The primary mechanism of action involves the disruption of METTL2A expression, leading to alterations in RNA modifications that can significantly impact gene expression profiles. This allows researchers to explore the physiological and pathological consequences of METTL2A loss in diverse biological contexts, such as cancer, neurodegenerative diseases, and cellular response to environmental stresses. The precise targeting provided by CRISPR/Cas9 technology ensures specific gene disruption, minimizing off-target effects and enabling accurate experimental results.
Scientifically, METTL2A Gene Knockout Cell Lines hold considerable importance, particularly in understanding the underlying mechanisms of RNA modification-related diseases. These models are valuable in both basic and applied research settings, facilitating the development of novel therapeutic strategies that target RNA metabolism and post-transcriptional regulation.
In comparison to traditional knockdown approaches, which often result in incomplete gene silencing, our knockout cell lines offer a definitive means of investigating METTL2A function without residual activity. This clear-cut approach provides researchers with greater confidence in their findings, allowing for more robust conclusions.
For researchers, clinicians, and institutions focused on molecular biology and therapeutics, METTL2A Gene Knockout Cell Lines stand as indispensable tools that enhance experimental rigor and drive innovation. Our company specializes in producing high-quality biological products backed by extensive scientific knowledge and rigorous quality control processes, ensuring that our offerings meet the diverse needs of the research community.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.