Gene: METTL22
Official Full Name: methyltransferase 22, Kin17 lysineprovided by HGNC
Gene Summary: This gene encodes a member of the non-histone lysine methyltransferases. It interacts with its substrate, Kin17, which is involved in DNA repair and replication and mRNA processing. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16220 | METTL22 Knockout cell line (HeLa) | Human | METTL22 | 1:3~1:6 | Negative | Online Inquiry |
KO16221 | METTL22 Knockout cell line (HCT 116) | Human | METTL22 | 1:2~1:4 | Negative | Online Inquiry |
KO16222 | METTL22 Knockout cell line (HEK293) | Human | METTL22 | 1:3~1:6 | Negative | Online Inquiry |
KO16223 | METTL22 Knockout cell line (A549) | Human | METTL22 | 1:3~1:4 | Negative | Online Inquiry |
METTL22 Gene Knockout Cell Lines represent a valuable technological advancement in the field of molecular biology and genetics, specifically designed to facilitate the in-depth study of gene function and regulation. These cell lines are engineered to have disruptions in the METTL22 gene, a methyltransferase known to play critical roles in RNA modification and cellular stress responses. By employing the CRISPR-Cas9 genome editing technology, these knockout cell lines provide researchers with robust tools to investigate the physiological and pathological implications of METTL22 absence.
The key mechanism of METTL22 Gene Knockout Cell Lines lies in their ability to allow for the functional analysis of METTL22, aiding in research around its contributions to RNA metabolic processes, gene expression, and potential roles in various diseases, including cancer and neurodegenerative disorders. This specific knockout facilitates unbiased studies on downstream effects of RNA methylation and opens up avenues for therapeutic interventions based on modulation of METTL22 pathways.
Scientifically, METTL22 knockout models are indispensable in both research and clinical settings, enabling the exploration of gene interactions and the development of novel approaches for gene therapy. Their application spans diverse fields including oncology, immunology, and neurobiology, where understanding the subtleties of gene function can lead to breakthroughs in treatment paradigms.
Compared to existing alternatives, the METTL22 Gene Knockout Cell Lines offer unparalleled precision and specificity in targeting the METTL22 gene, reducing off-target effects and providing a more reliable platform for experimentation. These constructs are validated and optimized for various research applications, making them a preferred choice for laboratories seeking to optimize their gene editing endeavors.
For researchers, clinicians, and biotechnologists, the value of METTL22 Gene Knockout Cell Lines lies in their ability to accelerate scientific discovery while providing insights that have the potential for clinical translation. With a commitment to innovation and quality, our company underscores its expertise in producing biological products that empower research communities to advance human health and biomedical knowledge.
Please note that all services are for research use only. Not intended for any clinical use.
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