Gene: METTL21A
Official Full Name: methyltransferase 21A, HSPA lysineprovided by HGNC
Gene Summary: Enables ATPase binding activity; Hsp70 protein binding activity; and protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine methylation. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22001 | METTL21A Knockout cell line (HeLa) | Human | METTL21A | 1:3~1:6 | Negative | Online Inquiry |
KO22002 | METTL21A Knockout cell line (HCT 116) | Human | METTL21A | 1:2~1:4 | Negative | Online Inquiry |
KO22003 | METTL21A Knockout cell line (HEK293) | Human | METTL21A | 1:3~1:6 | Negative | Online Inquiry |
KO22004 | METTL21A Knockout cell line (A549) | Human | METTL21A | 1:3~1:4 | Negative | Online Inquiry |
METTL21A Gene Knockout Cell Lines are a sophisticated, genetically modified model system that allows researchers to investigate the functional role of the METTL21A gene in various biological processes. These cell lines are engineered to have a targeted knockout of the METTL21A gene, enabling the study of gene function and associated pathways by eliminating its expression. This innovative tool plays a crucial role in elucidating how METTL21A contributes to cellular metabolism, differentiation, and response to environmental stimuli.
The primary mechanism of action involves the use of CRISPR-Cas9 technology, which precisely induces double-strand breaks at the METTL21A gene locus. The subsequent repair processes lead to frameshift mutations that result in a loss of function. By utilizing these knockout cell lines, researchers can assess the downstream effects on gene expression profiles, protein interactions, and metabolic pathways, greatly enhancing our understanding of the gene's biological significance.
Scientifically, METTL21A has been implicated in various diseases, including cancer and neurodegenerative disorders, making these knockout cell lines indispensable in both basic research and translational applications. They provide valuable insights for drug development, target validation, and understanding disease mechanisms at a molecular level.
When compared to traditional knockout models, such as whole organism knockouts, METTL21A Gene Knockout Cell Lines offer a more controlled environment that significantly reduces variability. They allow for rapid screening and high-throughput experimentation, making them a cost-effective option for researchers aiming to expedite their findings.
In summary, adopting METTL21A Gene Knockout Cell Lines can enhance the precision and efficiency of scientific research, providing researchers and clinicians with a powerful tool for advancing their studies. Our company is dedicated to delivering high-quality biological products backed by rigorous scientific validation, ensuring that our customers have access to cutting-edge tools that propel their research endeavors forward.
Please note that all services are for research use only. Not intended for any clinical use.
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